Surface functionalization of quantum dots for biological applications

被引：215

作者：

Karakoti, Ajay Singh ^{[1
]}

Shukla, Ritesh ^{[2
]}

Shanker, Rishi ^{[2
]}

Singh, Sanjay ^{[2
]}

机构：

[1] Battelle Sci & Technol India Pvt Ltd, Pune 411057, Maharashtra, India

[2] Ahmedabad Univ, Sch Sci & Technol, Inst Life Sci, Ahmadabad 380009, Gujarat, India

来源：

ADVANCES IN COLLOID AND INTERFACE SCIENCE | 2015年 / 215卷

关键词：

Quantum dots; Surface modifications; Imaging; Covalent coupling; Silanization; HYDROPHILIC BLOCK-COPOLYMER; RESONANCE ENERGY-TRANSFER; CLICK CHEMISTRY; GOLD NANOPARTICLES; PHASE-TRANSFER; LIVE CELL; IN-VITRO; MAGNETIC NANOPARTICLES; DRUG-DELIVERY; CDSE;

D O I：

10.1016/j.cis.2014.11.004

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Quantum dots are a group of inorganic nanomaterials exhibiting exceptional optical and electronic properties which impart distinct advantages over traditional fluorescent organic dyes in terms of tunable broad excitation and narrow emission spectra, signal brightness, high quantum yield and photo-stability. Aqueous solubility and surface functionalization are the most common problems for QDs employed in biological research. This review addresses the recent research progress made to improve aqueous solubility, functionalization of biomolecules to QD surface and the poorly understood chemistry involved in the steps of bio-functionalization of such nanoparticles. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：28 / 45

页数：18

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