A strategy to introduce the pH sensitivity to temperature sensitive PNIPAAm hydrogels without weakening the thermosensitivity

被引：51

作者：

Xu, Xiao-Ding

Zhang, Xian-Zheng ^{[1
]}

Cheng, Si-Xue

Zhuo, Ren-Xi

Kennedy, John F.

机构：

[1] Wuhan Univ, Key Lab Biomed Polymers, Minist Educ, Wuhan 430072, Peoples R China

[2] Wuhan Univ, Dept Chem, Wuhan 430072, Peoples R China

[3] Univ Birmingham, Chembiotech Labs, Birmingham B15 2SQ, W Midlands, England

来源：

CARBOHYDRATE POLYMERS | 2007年 / 68卷 / 03期

基金：

中国国家自然科学基金;

关键词：

hydrogel; thermosensitive; pH sensitive;

D O I：

10.1016/j.carbpol.2006.11.019

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A series of novel pH and thermosensitive hydrogels, comprised of N-isopropylacrylamide (NIPAAm) and N-isopropyl-maleamic acid (NIPMMA) units were designed and fabricated. The resultant P(NIPAAm-co-NIPMMA) hydrogels were characterized and it was found, with the increasing content of NIPMMA, that the pH sensitivity of P(NIPAArn-co-NIPMMA) hydrogel improved, whilst the temperature sensitivity remained almost the same. This unique intelligent character was attributed to the existence of a continuous isopropylamide sequence in P(NIPAAm-co-NIPMMA) hydrogels. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：416 / 423

页数：8

共 37 条

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