Extractive spectrophotometric determination of gatifloxacin

被引：0

作者：

Prasad, KVS ^{[1
]}

Prabhakar, G ^{[1
]}

Rao, SVMM ^{[1
]}

Sandhya, M ^{[1
]}

Jagganath, G ^{[1
]}

机构：

[1] Andhra Univ, Dept Pharmaceut Sci, Waltair 530003, Andhra Pradesh, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2003年 / 15卷 / 02期

关键词：

spectrophotometric determination; gatifloxacin;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three simple and sensitive extractive spectrophotometric methods (A-C) have been developed for the determination of gatifloxacin (GTL) in bulk drug and pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable complexes of drug with wool-fast blue BL (WFB BL lambda(max) 590 nm, Tropaeolineooo (Tp(000), lambda(max) 480nm) and bromo phenol blue (BPB lambda(max) 420 nm) in acidic medium. Beer's law is obeyed in the concentration ranges of 1-6 mug/mL, 1-6 mug/mL, and 2-10 mug/mL respectively. The results of analysis for all three methods have been validated statistically and by recovery studies.

引用

页码：1170 / 1172

页数：3