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Guangdong Acad Med Sci, Guangdong Prov Inst Geriatr, Guangdong Gen Hosp, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China Guangdong Acad Med Sci, Guangdong Prov Inst Geriatr, Guangdong Gen Hosp, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China