Phase I Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis

被引：62

作者：

Bonini, Stefano ^{[1
]}

Lambiase, Alessandro ^{[2
]}

Rama, Paolo ^{[3
]}

Filatori, Isabella ^{[4
]}

Allegretti, Marcello ^{[4
]}

Chao, Wendy ^{[4
]}

Mantelli, Flavio ^{[4
]}

机构：

[1] Campus Biomed Univ, Dept Ophthalmol, Rome, Italy

[2] Sapienza Univ, Sense Organs Dept, Viale Policlin 155, I-00100 Rome, Italy

[3] Ist Sci San Raffaele, Milan, Italy

[4] Dompe Farmaceut SpA, Milan, Italy

来源：

OPHTHALMOLOGY | 2018年 / 125卷 / 09期

关键词：

D O I：

10.1016/j.ophtha.2018.03.004

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

[No abstract available]

引用

页码：1468 / 1471

页数：4

共 5 条

[1] Phase II Randomized, Double-Masked, Vehicle-Controlled Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis [J].

Bonini, Stefano ;

Lambiase, Alessandro ;

Rama, Paolo ;

Sinigaglia, Francesco ;

Allegretti, Marcello ;

Chao, Wendy ;

Mantelli, Flavio .

OPHTHALMOLOGY, 2018, 125 (09) :1332-1343

[2] Safety and Pharmacokinetics of Escalating Doses of Human Recombinant Nerve Growth Factor Eye Drops in a Double-Masked, Randomized Clinical Trial [J].

Ferrari, Mauro P. ;

Mantelli, Flavio ;

Sacchetti, Marta ;

Antonangeli, Maria Irene ;

Cattani, Franca ;

D'Anniballe, Gaetano ;

Sinigaglia, Francesco ;

Ruffini, Pier Adelchi ;

Lambiase, Alessandro .

BIODRUGS, 2014, 28 (03) :275-283

[3]

Lambiase A, 2011, ARCH ITAL BIOL, V149, P283, DOI 10.4449/aib.v149i2.1363

[4] Topical treatment with nerve growth factor for corneal neurotrophic ulcers [J].

Lambiase, A ;

Rama, P ;

Bonini, S ;

Caprioglio, G ;

Aloe, L .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (17) :1174-1180

[5] Understanding the Pathogenesis of Neurotrophic Keratitis: The Role of Corneal Nerves [J].

Mastropasqua, Leonardo ;

Massaro-Giordano, Giacomina ;

Nubile, Mario ;

Sacchetti, Marta .

JOURNAL OF CELLULAR PHYSIOLOGY, 2017, 232 (04) :717-724

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