Ansellone A, a Sesterterpenoid Isolated from the Nudibranch Cadlina luteromarginata and the Sponge Phorbas sp., Activates the cAMP Signaling Pathway

被引：43

作者：

Daoust, Julie ^{[3
,4
]}

Fontana, Angelo ^{[3
,4
]}

Merchant, Catherine E. ^{[1
]}

de Voogd, Nicole J. ^{[2
]}

Patrick, Brian O. ^{[3
]}

Kieffer, Timothy J. ^{[1
]}

Andersen, Raymond J. ^{[3
,4
]}

机构：

[1] Univ British Columbia, Dept Cellular & Physiol Sci & Surg, Vancouver, BC V6T 1Z3, Canada

[2] Netherlands Ctr Biodivers Naturalis, NL-2300 RA Leiden, Netherlands

[3] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

[4] Univ British Columbia, Dept Earth & Ocean Sci, Vancouver, BC V6T 1Z1, Canada

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 14期

基金：

加拿大自然科学与工程研究理事会;

关键词：

CARBON SKELETON; LUTEOMARGINATA;

D O I：

10.1021/ol101151f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ansellone A (1) has ben isolated from the dorid nudibranch Cadlina luteomarginata and the sponge Phorbas sp. It has the new "ansellane" sesterterpenoid carbon skeleton, and it activates the cAMP signaling pathway.

引用

页码：3208 / 3211

页数：4

共 14 条

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