DNA interstrand crosslinks:: Natural and drug-induced DNA adducts that induce unique cellular responses

被引:158
作者
Schärer, OD [1 ]
机构
[1] Univ Zurich, Inst Mol Canc Res, CH-8008 Zurich, Switzerland
关键词
antitumor agents; cancer; DNA damage; DNA repair;
D O I
10.1002/cbic.200400287
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:27 / 32
页数:6
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共 72 条
[1]   Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells [J].
Abraham, J ;
Lemmers, B ;
Hande, MP ;
Moynahan, ME ;
Chahwan, C ;
Ciccia, A ;
Essers, J ;
Hanada, K ;
Chahwan, R ;
Khaw, AK ;
McPherson, P ;
Shehabeldin, A ;
Laister, R ;
Arrowsmith, C ;
Kanaar, R ;
West, SC ;
Jasin, M ;
Hakem, R .
EMBO JOURNAL, 2003, 22 (22) :6137-6147
[2]   DNA replication is required to elicit cellular responses to psoralen-induced DNA interstrand cross-links [J].
Akkari, YMN ;
Bateman, RL ;
Reifsteck, CA ;
Olson, SB ;
Grompe, M .
MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (21) :8283-8289
[3]  
ANGELOV T, UNPUB
[4]  
Baron Elma D, 2003, Dermatol Ther, V16, P303, DOI 10.1111/j.1396-0296.2003.01642.x
[5]   DNA polymerase II (polB) is involved in a new DNA repair pathway for DNA interstrand cross-links in Escherichia coli [J].
Berardini, M ;
Foster, PL ;
Loechler, EL .
JOURNAL OF BACTERIOLOGY, 1999, 181 (09) :2878-2882
[6]   Induction of DNA replication-mediated double strand breaks by psoralen DNA interstrand cross-links [J].
Bessho, T .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (07) :5250-5254
[7]   Deoxyadenosine and thymidine bases held proximal and distal by means of a covalently-linked dimensional analogue of dA center dot dT: Intramolecular vs intermolecular hydrogen bonding [J].
Bhat, B ;
Leonard, NJ ;
Robinson, H ;
Wang, AHJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (44) :10744-10751
[8]  
Bootsma D., 1998, The Genetic Basis of Human Cancer, P245
[9]   The switch from survival responses to apoptosis after chromosomal breaks [J].
Bree, RT ;
Neary, C ;
Samali, A ;
Lowndes, NF .
DNA REPAIR, 2004, 3 (8-9) :989-995
[10]   REACTION OF MUSTARD GAS WITH NUCLEIC ACIDS INVITRO AND INVIVO [J].
BROOKES, P ;
LAWLEY, PD .
BIOCHEMICAL JOURNAL, 1960, 77 :478-484