Short and flexible route to 3,4-diarylpyrrole marine alkaloids: syntheses of permethyl storniamide A, ningalin B, and lamellarin G trimethyl ether

被引：86
作者：
Iwao, M
Takeuchi, T
Fujikawa, N
Fukuda, T
Ishibashi, F
机构：
[1] Nagasaki Univ, Fac Engn, Dept Appl Chem, Nagasaki 8528521, Japan
[2] Nagasaki Univ, Div Marine Life Sci & Biochem, Nagasaki 8528521, Japan
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 24期
关键词：
D O I：
10.1016/S0040-4039(03)01031-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly efficient route to 3,4-diarylpyrrole marine alkaloids has been developed using Hinsberg-type pyrrole synthesis and palladium-catalyzed Suzuki cross-coupling of the 3,4-dihydroxypyrrole bis-triflate derivatives as key reactions. Based oil this approach. formal syntheses of permethyl storniamide A and ningalin B, and a total synthesis of lamellarin G trimethyl ether have been achieved. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：4443 / 4446
页数：4
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