Concise Synthesis of (-)-Nakadomarin A

被引：20

作者：

Martin, David B. C. ^{[1
]}

Vanderwal, Christopher D. ^{[1
]}

机构：

[1] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 16期

关键词：

alkaloids; organocatalysis; ring-closing metathesis; synthesis design; three-component coupling; ASYMMETRIC TOTAL-SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; NAKADOMARIN-A; DERIVATIVES; METATHESIS; MANZAMINE; CORE;

D O I：

10.1002/anie.201000045

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) The beautiful orchestration of new methods and synthesis design was instrumental to the very efficient synthesis of the manzamine alkaloid (-) -nakadomarin A. In only six operations, the two relatively simple compounds shown were converted into the hexacyclic natural product.© 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2830 / 2832

页数：3

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