Differences in the time course of splenial and white matter lesions in clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS)

被引:83
作者
Takanashi, Jun-ichi [1 ]
Imamura, Atsushi [2 ]
Hayakawa, Fumio [3 ]
Terada, Hitoshi [4 ]
机构
[1] Kameda Med Ctr, Dept Pediat, Kamogawa, Chiba 2968602, Japan
[2] Gifu Prefectural Gen Med Ctr, Dept Pediat, Gifu, Japan
[3] Okazaki City Hosp, Dept Pediat, Okazaki, Aichi, Japan
[4] Toho Univ, Sakura Med Ctr, Dept Radiol, Sakura, Japan
关键词
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS); MRI; Diffusion; Splenium; White matter; ENCEPHALOPATHY; INFLUENZA;
D O I
10.1016/j.jns.2010.02.013
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Two patients with clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) exhibiting lesions in the white matter and entire corpus callosum (type 2) are reported. The time course differed between the splenial lesion and other lesions in the white matter and corpus callosum other than the splenium: the latter disappeared earlier than the former. These findings strongly suggest that MERS type 2 resolves completely through MERS type 1 exhibiting an isolated splenial lesion, and MERS types 1 and 2 have the same pathophysiology. The possible prior white matter lesions in patients with MERS type 1 may explain the neurological symptoms or EEG abnormalities. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:24 / 27
页数:4
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