Not every polymorphism close to the AUG codon can be explained by invoking context effects on initiation of translation

被引：14

作者：

Kozak, M ^{[1
]}

机构：

[1] Robert Wood Johnson Med Sch, Dept Biochem, Piscataway, NJ 08854 USA

来源：

BLOOD | 2003年 / 101卷 / 03期

关键词：

D O I：

10.1182/blood-2002-10-3194

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1202 / 1203

页数：2

共 11 条

[1] A common polymorphism in the annexin V Kozak sequence (-1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients [J].

González-Conejero, R ;

Corral, J ;

Roldán, V ;

Martínez, C ;

Marín, F ;

Rivera, J ;

Iniesta, JA ;

Lozano, ML ;

Marco, P ;

Vicente, V .

BLOOD, 2002, 100 (06) :2081-2086

[2] AT LEAST 6 NUCLEOTIDES PRECEDING THE AUG INITIATOR CODON ENHANCE TRANSLATION IN MAMMALIAN-CELLS [J].

KOZAK, M .

JOURNAL OF MOLECULAR BIOLOGY, 1987, 196 (04) :947-950

[3] EVALUATION OF THE FIDELITY OF INITIATION OF TRANSLATION IN RETICULOCYTE LYSATES FROM COMMERCIAL SOURCES [J].

KOZAK, M .

NUCLEIC ACIDS RESEARCH, 1990, 18 (09) :2828-2828

[4] Pushing the limits of the scanning mechanism for initiation of translation [J].

Kozak, M .

GENE, 2002, 299 (1-2) :1-34

[5] Emerging links between initiation of translation and human diseases [J].

Kozak, M .

MAMMALIAN GENOME, 2002, 13 (08) :401-410

[6] DOWNSTREAM SECONDARY STRUCTURE FACILITATES RECOGNITION OF INITIATOR CODONS BY EUKARYOTIC RIBOSOMES [J].

KOZAK, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (21) :8301-8305

[7] Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6 [J].

Kozak, M .

EMBO JOURNAL, 1997, 16 (09) :2482-2492

[8] Initiation of translation in prokaryotes and eukaryotes [J].

Kozak, M .

GENE, 1999, 234 (02) :187-208

[9] POINT MUTATIONS DEFINE A SEQUENCE FLANKING THE AUG INITIATOR CODON THAT MODULATES TRANSLATION BY EUKARYOTIC RIBOSOMES [J].

KOZAK, M .

CELL, 1986, 44 (02) :283-292

[10]

NEUFELD E, 2002, BLOOD, V100, P1933

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