Oxidative cleavage of benzylic C-N bonds under metal-free conditions

被引：29

作者：

Gong, Jin-Long ^{[1
]}

Qi, Xinxin ^{[1
]}

Wei, Duo ^{[1
]}

Feng, Jian-Bo ^{[1
]}

Wu, Xiao-Feng ^{[1
,2
]}

机构：

[1] Zhejiang Sci Tech Univ, Dept Chem, Hangzhou 310018, Zhejiang, Peoples R China

[2] Univ Rostock, Leibniz Inst Katalyse, D-18059 Rostock, Germany

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 38期

关键词：

ZINC-CATALYZED OXIDATION; ALLYLIC SULFONYLATION; ALCOHOLS; ALDEHYDES; ESTERIFICATION; BENZAMIDES; AMIDATION; SULFONYLHYDRAZIDES; C3-FORMYLATION; AMINATION;

D O I：

10.1039/c4ob01633e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An interesting procedure for the oxidative cleavage of benzylic C-N bonds has been developed. Using TBAI as the catalyst and H2O2 as the oxidant, various benzylamines were transformed into their corresponding aromatic aldehydes in moderate to good yields. Notably, this is the first example of an oxidative cleavage of benzylic C-N bonds under metal-free conditions.

引用

页码：7486 / 7488

页数：3

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