Quantitative immunohistochemistry in lung cancer: clinical perspective

被引:6
|
作者
Szutowicz, Ewa [1 ]
Dziadziuszko, Rafal [1 ]
机构
[1] Med Acad Gdansk, Dept Radiotherapy & Oncol, PL-80211 Gdansk, Poland
关键词
lung cancer; immunohistochemistry; clinical trials; protein expression; FACTOR RECEPTOR EXPRESSION; TRIAL BIOLOGIC PROGRAM; ADJUVANT CHEMOTHERAPY; PREDICT BENEFIT; CELL; SURVIVAL; GEFITINIB; CISPLATIN; ERLOTINIB; ERCC1;
D O I
10.2478/v10042-010-0014-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Quantitative immunohistochemistry remains an important tool in translational lung cancer research with hopes to improve patient outcomes and avoid unnecessary therapies. Present review is aimed to summarize the use of immunohistochemical markers for improved prognostic information and prediction of treatment benefit. Several of these markers are currently explored in phase II - III clinical studies to individualize the treatment of lung cancer.
引用
收藏
页码:7 / 11
页数:5
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