Endometrial carcinoma

被引:0
作者
Schindelhauer, Axel [1 ]
Wimberger, Pauline [1 ]
机构
[1] Tech Univ Dresden, Klin & Poliklin Gynakol & Geburtshilfe, Fetscherstr 74, D-01307 Dresden, Germany
来源
ONKOLOGE | 2020年 / 26卷 / 02期
关键词
Uterine neoplasms; Hysteroscopy; Hysterectomy; Salpingo-oophorectomy; Chemotherapy; adjuvant; CANCER; TRIAL; RISK;
D O I
10.1007/s00761-019-00669-6
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Endometrial carcinoma is the most common gynecological cancer in Germany. It has a good prognosis. Drug therapies, lifestyle, and nutrition are important regarding prevention. In atypical bleeding, sonographic evaluation of the endometrium, hysteroscopy, and dilation and curettage play an important role in early detection. The diagnosis of endometrial carcinoma begins with histology, which allows determination of carcinoma type and grading. It is supplemented by staging, where deep infiltration, resectability and metastasis are decisive for therapy. In type I carcinoma, hysterectomy with bilateral salpingo-oophorectomy is the treatment of choice. In type II carcinoma, this procedure is supplemented by omentectomy and peritoneal biopsies. Patients with advanced tumor stages benefit from adjuvant chemotherapy. With increasing grade, vaginal brachytherapy is useful to reduce the risk of local recurrence.
引用
收藏
页码:187 / 200
页数:14
相关论文
共 50 条
  • [41] Adjuvant Radiation Therapy for Patients With Type II Endometrial Carcinoma Impact on Tumor Recurrence and Survival
    Yechieli, Raphael
    Rasool, Nabila
    Robbins, Jared R.
    Cogan, Chad M.
    Elshaikh, Mohamed A.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2013, 23 (04) : 763 - 768
  • [42] Morphometric and DNA Image Analysis of Endometrial Hyperplasia and Carcinoma
    El-Sharkawy, Sonia L.
    Abbas, Naglaa F.
    El-Henawy, Ahmed M. Y.
    Badawi, Manal A. El-Megeed
    Yasseen, Noha N.
    APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2017, 25 (01) : 32 - 38
  • [43] Proteogenomic insights suggest druggable pathways in endometrial carcinoma
    Dou, Yongchao
    Katsnelson, Lizabeth
    Gritsenko, Marina A.
    Hu, Yingwei
    Reva, Boris
    Hong, Runyu
    Wang, Yi-Ting
    Kolodziejczak, Iga
    Lu, Rita Jui-Hsien
    Tsai, Chia-Feng
    Bu, Wen
    Liu, Wenke
    Guo, Xiaofang
    An, Eunkyung
    Arend, Rebecca C.
    Bavarva, Jasmin
    Chen, Lijun
    Chu, Rosalie K.
    Czekanski, Andrzej
    Davoli, Teresa
    Demicco, Elizabeth G.
    Delair, Deborah
    Devereaux, Kelly
    Dhanasekaran, Saravana M.
    Dottino, Peter
    Dover, Bailee
    Fillmore, Thomas L.
    Foxall, McKenzie
    Hermann, Catherine E.
    Hiltke, Tara
    Hostetter, Galen
    Jedryka, Marcin
    Jewell, Scott D.
    Johnson, Isabelle
    Kahn, Andrea G.
    Ku, Amy T.
    Kumar-Sinha, Chandan
    Kurzawa, Pawel
    Lazar, Alexander J.
    Lazcano, Rossana
    Lei, Jonathan T.
    Li, Yi
    Liao, Yuxing
    Lih, Tung-Shing M.
    Lin, Tai-Tu
    Martignetti, John A.
    Masand, Ramya P.
    Matkowski, Rafal
    Mckerrow, Wilson
    Mesri, Mehdi
    CANCER CELL, 2023, 41 (09) : 1586 - +
  • [44] Clinical significance of pmTOR expression in endometrioid endometrial carcinoma
    Choi, Chel Hun
    Lee, Ji-Soo
    Kim, Seong Rim
    Kim, Tae-Joong
    Lee, Jeong-Won
    Kim, Byoung-Gie
    Bae, Duk-Soo
    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2010, 153 (02) : 207 - 210
  • [45] Immune Subtypes and Immune Landscape Analysis of Endometrial Carcinoma
    Liang, Leilei
    Zhu, Yunshu
    Li, Jian
    Zeng, Jia
    Yuan, Guangwen
    Wu, Lingying
    JOURNAL OF IMMUNOLOGY, 2022, 209 (08) : 1606 - 1614
  • [46] Predictors of Bilateral SLN Radiocolloid Detection in Endometrial Carcinoma
    Jankulovska, Anamarija
    Stojcevski, Sasho
    Aluloski, Igor
    Tanturovski, Mile
    Manevska, Nevena
    Markova, Ana Daneva
    Stojanoski, Sinisa
    WORLD JOURNAL OF NUCLEAR MEDICINE, 2023, 22 (04) : 261 - 266
  • [47] POLE Mutation Characteristics in a Chinese Cohort with Endometrial Carcinoma
    Li, Yiran
    He, Qizhi
    Li, Shuangdi
    Wen, Xiaoli
    Ye, Lei
    Wang, Kai
    Wan, Xiaoping
    ONCOTARGETS AND THERAPY, 2020, 13 : 7305 - 7316
  • [48] Clinicopathologic Analysis of Matched Primary and Recurrent Endometrial Carcinoma
    Soslow, Robert A.
    Wethington, Stephanie L.
    Cesari, Matthew
    Chiappetta, Daniel
    Olvera, Narciso
    Shia, Jinru
    Levine, Douglas A.
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2012, 36 (12) : 1771 - 1781
  • [49] Paclitaxel, Carboplatin, and Bevacizumab in Advanced and Recurrent Endometrial Carcinoma
    Rose, Peter G.
    Ali, Shamshad
    Moslemi-Kebria, Mehdi
    Simpkins, Fiona
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2017, 27 (03) : 452 - 458
  • [50] Prediction of concurrent endometrial carcinoma in women with endometrial hyperplasia
    Matsuo, Koji
    Ramzan, Amin A.
    Gualtieri, Marc R.
    Mhawech-Fauceglia, Paulette
    Machida, Hiroko
    Moeini, Aida
    Dancz, Christina E.
    Ueda, Yutaka
    Roman, Lynda D.
    GYNECOLOGIC ONCOLOGY, 2015, 139 (02) : 261 - 267