Objectives. Our community-academic partnership employed community-based participatory research to develop and pilot a simple, peer-led intervention to promote weight loss, which can prevent diabetes and eliminate racial/ethnic disparities in incident diabetes among overweight adults with prediabetes. Methods. We recruited overweight adults at community sites, performed oral glucose tolerance testing to identify persons with blood glucose levels in the prediabetes range, and randomized eligible people to a peer-led lifestyle intervention group or delayed intervention in 1 year. Outcomes, including weight, blood pressure, and health behaviors, were measured at baseline and 3, 6, and 12 months. Results. More than half of those tested (56%, or 99 of 178) had prediabetes and enrolled in the study. Participants were predominantly Spanish-speaking, low-income, undereducated women. The intervention group lost significantly more weight than the control group and maintained weight loss at 12 months (7.2 versus 2.4 pounds; P<.01). One fourth (24 of 99) of participants progressed to diabetes. Conclusions. In underserved minority communities, prediabetes prevalence may be higher than previously reported. Low-cost, community-based interventions can succeed in encouraging weight loss to prevent diabetes. (Am J Public Health. 2010;100:S232-S239. doi:10.2105/AJPH.2009.170910)
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Stanford Univ, Sch Med, Palo Alto, CA 94304 USAStanford Univ, Sch Med, Palo Alto, CA 94304 USA
Lorig, Kate
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Villa, Frank
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Univ Michigan, Div Gen Med, Ann Arbor, MI 48109 USA
Ctr Practice Management & Outcomes Res, VA Hlth Serv Res & Dev Serv Ctr Excellence, Ann Arbor, MI 48109 USAStanford Univ, Sch Med, Palo Alto, CA 94304 USA
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Stanford Univ, Sch Med, Palo Alto, CA 94304 USAStanford Univ, Sch Med, Palo Alto, CA 94304 USA
Lorig, Kate
Ritter, Philip L.
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Stanford Univ, Sch Med, Palo Alto, CA 94304 USAStanford Univ, Sch Med, Palo Alto, CA 94304 USA
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Villa, Frank
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Stanford Univ, Sch Med, Palo Alto, CA 94304 USAStanford Univ, Sch Med, Palo Alto, CA 94304 USA
Villa, Frank
Piette, John D.
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Univ Michigan, Div Gen Med, Ann Arbor, MI 48109 USA
Ctr Practice Management & Outcomes Res, VA Hlth Serv Res & Dev Serv Ctr Excellence, Ann Arbor, MI 48109 USAStanford Univ, Sch Med, Palo Alto, CA 94304 USA