Para-Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes

被引：8

作者：

Berger, Michael ^{[1
]}

Lenhard, Marola S. ^{[1
]}

Waldvogel, Siegfried R. ^{[1
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Dept Chem, Duesbergweg 10-14, D-55128 Mainz, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2022年 / 28卷 / 41期

关键词：

anilides; electrochemistry; electrosynthesis; fluorination; hypervalent iodine; ELECTROLYTIC PARTIAL FLUORINATION; DOPED DIAMOND ELECTRODES; SELECTIVE FLUORINATION; ORGANIC-COMPOUNDS; ELECTROSYNTHESIS; DIFLUORIDE;

D O I：

10.1002/chem.202201029

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The para-selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF2 is reported, with Et3N center dot 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set-up, easy scalability and affords a broad variety of fluorinated anilides from easily accessible anilides in good yields up to 86 %.

引用

页数：5

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