Bleeding risk with Ketorolac after lumbar microdiscectomy

被引:21
作者
Chin, Kingsley R.
Sundram, Hariharan
Marcotte, Paid
机构
[1] Univ Penn, Sch Med, Dept Orthopaed, Spine Surg Serv, Philadelphia, PA 19104 USA
[2] Univ Penn, Sch Med, Dept Anesthesia, Philadelphia, PA 19104 USA
[3] Univ Penn, Sch Med, Dept Neurosurg, Philadelphia, PA 19104 USA
来源
JOURNAL OF SPINAL DISORDERS & TECHNIQUES | 2007年 / 20卷 / 02期
关键词
microdiscectomy; minimal invasive surgery; Toradol; analgesia; complications; hemostasis; epidural bleed; POSTOPERATIVE HEMORRHAGE; TROMETHAMINE; TONSILLECTOMY; SURGERY; PAIN;
D O I
10.1097/01.bot.0000211163.51605.ae
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
There is a need to improve postoperative analgesia to support the trend to shorter hospitalization after minimally invasive spine surgeries. Ketorolac Tromethamine has proven efficacy in decreasing postoperative pain but there is concern with postoperative epidural bleeding after spine procedures. We prospectively assessed the incidence of bleeding complications after microdiscectomy in patients treated with a single 30 mg intraoperative dose of Ketorolac subsequent to wound closure. Group 1 consisted of 44 patients, 24 women and 20 men with mean age of 35.7 years (20 to 68 y) treated With Ketorolac. Group 2 consisted of 45 patients, 28 men and 17 women with mean age 46.8 years (32 to 74 y), who underwent discectomy without Ketorolac. Postoperative bleeding complications were monitored along with pain levels and time to discharge. We detected no significant postoperative changes in coagulation parameters or bleeding from the surgical site in either group. Both group 1 and 2 had averaged preoperative visual analog scale scores for leg pain of 8. Group 1 had an average postoperative visual analog scale score of 2.6 compared with 4 for group 2 two hours after surgery. Single dose intravenous Ketorolac provided beneficial analgesia without significant increase in risk of bleeding after microdiscectomy, enabling us to consistently perform microdiscectomy as an ambulatory procedure. Meticulous hemostasis should be accomplished before closure. Prolonged postoperative use is a promising alternative to narcotics.
引用
收藏
页码:123 / 126
页数:4
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