Effects of the components of hormone therapy on matrix metalloproteinases in breast-cancer cells: an in vitro study

被引：7
作者：
Abdallah, Maher A.
Abdullah, Huda I.
Kang, Steven
Taylor, Douglas D.
Nakajima, Steven T.
Gercel-Taylor, Cicek
机构：
[1] Univ Louisville, Sch Med, Dept Obstet Gynecol & Womens Hlth, Div Reprod Endocrinol, Louisville, KY 40202 USA
[2] New York Med Coll, Valhalla, NY USA
[3] Univ Louisville, Sch Med, Dept Obstet Gynecol & Womens Hlth, Div Gynecol Oncol, Louisville, KY 40202 USA
来源：
FERTILITY AND STERILITY | 2007年 / 87卷 / 04期
关键词：
D O I：
10.1016/j.fertnstert.2006.08.091
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
A combination of E and progestogens significantly increased matrix metalloproteinase (MMP)-2 in both T47D cells (E-2-medroxyprogesteroneacetate [MPA] and E-2-P) and MCF-7 cells (E-2-MPA, E-2-P, and equilin-MPA). All combinations resulted in higher MMP-9 levels in MCF-7 cells, but higher MMP-9 levels resulted only with equilin-norethinderone in T47D cells.
引用
收藏
页码：978 / 981
页数：4
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