Green synthesis, characterization and antibacterial evaluation of electrospun nickel oxide nanofibers

被引：37

作者：

Ramalingam, Raghavendra ^{[1
,2
]}

Fazil, Mobashar Hussain Urf Turabe ^{[3
]}

Verma, Navin Kumar ^{[3
,4
]}

Arunachalam, Kantha Deivi ^{[1
]}

机构：

[1] SRM Inst Sci & Technol, Ctr Environm Nucl Res, Kattankulathur 603203, Tamil Nadu, India

[2] SRM Inst Sci & Technol, Dept Phys & Nanotechnol, Kattankulathur 603203, Tamil Nadu, India

[3] Nanyang Technol Univ Singapore, Lee Kong Chian Sch Med, Expt Med Bldg,59 Nanyang Dr, Singapore 636921, Singapore

[4] Acad, Singapore Eye Res Inst, Antiinfect Res Grp, 20 Coll Rd,Discovery Tower, Singapore 169856, Singapore

来源：

MATERIALS LETTERS | 2019年 / 256卷

关键词：

Nanoparticles; Gelatin; Pol-epsilon-caprolactone; Electrospun hybrid mats; Gymnema sylvestre; Biomaterials; NIO; NANOPARTICLES; EXTRACT; GROWTH; CYTOTOXICITY; TOXICITY;

D O I：

10.1016/j.matlet.2019.126616

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Bacterial infection followed by biofilm formation at the site of injury presents an extensive and tenacious challenge to wound care management as it leads to delayed wound healing. Recently nanoparticles and nanofibers have been widely investigated for their superior physical and biological supportive properties. This study presents the green synthesis of nickel oxide nanoparticles using Gymnema sylvestre extracts. The synthesized nanoparticles were infused into electrospun poly-epsilon-caprolactone/Gelatin hybrid nanofibrous mats. As synthesized nanofibrous mats exhibited good wettability, enhanced mechanical properties, biocompatibility and potent antibacterial activity. Overall, the bio functionalized nickel oxide nanoparticles infused electrospun nanofibrous mats can serve as an effective anti-infective wound dressing. (C) 2019 Elsevier B.V. All rights reserved.

引用

页数：5

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