Replacing Sedentary Time with Physical Activity in Relation to Mortality

被引:98
作者
Schmid, Daniela [1 ]
Ricci, Cristian [1 ]
Baumeister, Sebastian E. [1 ,2 ]
Leitzmann, Michael F. [1 ]
机构
[1] Univ Regensburg, Dept Epidemiol & Prevent Med, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany
[2] Univ Med Greifswald, Inst Community Med, Greifswald, Germany
关键词
PHYSICAL ACTIVITY; SEDENTARY BEHAVIOR; ACCELEROMETRY; ISOTEMPORAL SUBSTITUTION; MORTALITY; ALL-CAUSE MORTALITY; CARDIOVASCULAR-DISEASE; UNITED-STATES; SITTING TIME; EXERCISE; BEHAVIORS; ADULTS; HEALTH; SPENT; RISK;
D O I
10.1249/MSS.0000000000000913
中图分类号
G8 [体育];
学科分类号
04 ; 0403 ;
摘要
Introduction: Data evaluating mortality benefit from replacing sedentary time with physical activity are sparse. We explored reallocating time spent in sedentary behavior to physical activity of different intensities in relation to mortality risk. Methods: Women and men age 50-85 yr from the National Health and Nutrition Examination Survey 2003-2004 and 2005-2006 cycles with follow-up through December 31, 2011, were included. Sedentary time and physical activity were assessed using an ActiGraph accelerometer. Isotemporal substitution models were used to estimate the effect of replacing one activity behavior with another activity behavior for the same amount of time while holding total accelerometer wear time constant. Results: During a mean follow-up of 6.35 yr, 697 deaths from any cause occurred. Replacing 30 min of sedentary time with an equal amount of light activity was associated with 14% reduced risk of mortality (multivariable-adjusted hazard ratio (HR), 0.86; 95% confidence interval (CI), 0.83-0.90). Replacement of sedentary time with moderate to vigorous activity was related to 50% mortality risk reduction (HR, 0.50; 95% CI, 0.31-0.80). We also noted a 42% reduced risk of mortality when light physical activity was replaced by moderate to vigorous activity (HR, 0.58; 95% CI, 0.36-0.93). Conclusion: Replacing sedentary time with an equal amount of physical activity may protect against preterm mortality. Replacement of light physical activity with moderate to vigorous activity is also associated with protection from premature mortality.
引用
收藏
页码:1312 / 1319
页数:8
相关论文
共 42 条
  • [1] 2011 Compendium of Physical Activities: A Second Update of Codes and MET Values
    Ainsworth, Barbara E.
    Haskell, William L.
    Herrmann, Stephen D.
    Meckes, Nathanael
    Bassett, David R., Jr.
    Tudor-Locke, Catrine
    Greer, Jennifer L.
    Vezina, Jesse
    Whitt-Glover, Melicia C.
    Leon, Arthur S.
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2011, 43 (08) : 1575 - 1581
  • [2] Impact of 9 Days of Bed Rest on Hepatic and Peripheral Insulin Action, Insulin Secretion, and Whole-Body Lipolysis in Healthy Young Male Offspring of Patients With Type 2 Diabetes
    Alibegovic, Amra C.
    Hojbjerre, Lise
    Sonne, Mette P.
    van Hall, Gerrit
    Stallknecht, Bente
    Dela, Flemming
    Vaag, Allan
    [J]. DIABETES, 2009, 58 (12) : 2749 - 2756
  • [3] [Anonymous], QUEST DAT REL DOC
  • [4] Light-Intensity Physical Activities and Mortality in the United States General Population and CKD Subpopulation
    Beddhu, Srinivasan
    Wei, Guo
    Marcus, Robin L.
    Chonchol, Michel
    Greene, Tom
    [J]. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2015, 10 (07): : 1145 - 1153
  • [5] Impact of postprandial glycaemia on health and prevention of disease
    Blaak, E. E.
    Antoine, J. -M.
    Benton, D.
    Bjorck, I.
    Bozzetto, L.
    Brouns, F.
    Diamant, M.
    Dye, L.
    Hulshof, T.
    Holst, J. J.
    Lamport, D. J.
    Laville, M.
    Lawton, C. L.
    Meheust, A.
    Nilson, A.
    Normand, S.
    Rivellese, A. A.
    Theis, S.
    Torekov, S. S.
    Vinoy, S.
    [J]. OBESITY REVIEWS, 2012, 13 (10) : 923 - 984
  • [6] Calorie restriction modulates inactivity-induced changes in the inflammatory markers c-reactive protein and pentraxin-3
    Bosutti, Alessandra
    Malaponte, Grazia
    Zanetti, Michela
    Castellino, Pietro
    Heer, Martina
    Guarnieri, Gianfranco
    Biolo, Gianni
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2008, 93 (08) : 3226 - 3229
  • [7] Reexamination of validity and reliability of the CSA monitor in walking and running
    Brage, S
    Wedderkopp, N
    Franks, PW
    Andersen, LB
    Froberg, K
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2003, 35 (08) : 1447 - 1454
  • [8] Reallocating Time to Sleep, Sedentary Behaviors, or Active Behaviors: Associations With Cardiovascular Disease Risk Biomarkers, NHANES 2005-2006
    Buman, Matthew P.
    Winkler, Elisabeth A. H.
    Kurka, Jonathan M.
    Hekler, Eric B.
    Baldwin, Carol M.
    Owen, Neville
    Ainsworth, Barbara E.
    Healy, Genevieve N.
    Gardiner, Paul A.
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2014, 179 (03) : 323 - 334
  • [9] Objective vs. Self-Reported Physical Activity and Sedentary Time: Effects of Measurement Method on Relationships with Risk Biomarkers
    Celis-Morales, Carlos A.
    Perez-Bravo, Francisco
    Ibanez, Luis
    Salas, Carlos
    Bailey, Mark E. S.
    Gill, Jason M. R.
    [J]. PLOS ONE, 2012, 7 (05):
  • [10] Centers for Disease Control and Prevention Website, NCHS DAT LINK MORT F