Convenient and Efficient Method for the Synthesis of N-Heteroaryl Aminonaphthols under Solvent-Free Conditions

被引:22
|
作者
Olyaei, Abolfazi [1 ]
Raoufmoghaddam, Saeed [2 ]
Sadeghpour, Mahdieh [3 ]
Ebadzadeh, Behruz [1 ]
机构
[1] PNU, Dept Chem, Qazvin, Iran
[2] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran
[3] Islamic Azad Univ, Dept Chem, Takestan Branch, Qazvin, Iran
关键词
beta-naphthol; Betti base; solvent-free; heteroaryl amine; aminonaphthol; RICH AROMATIC-COMPOUNDS; ENANTIOSELECTIVE ADDITION; BETTI BASE; ONE-POT; ALDEHYDES; PHENOLS; AMINOALKYLATION; DERIVATIVES; DIETHYLZINC; LIGANDS;
D O I
10.1002/cjoc.201090153
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A convenient, efficient and green synthesis of N-heteroaryl aminonaphthols has been developed by one-pot, three-component condensation of beta-naphthol, heteroaryl amines and substituted benzaldehydes under solvent-free conditions at elevated temperature. The advantages of these reactions are simplicity of the reaction procedure, short reaction times, simple work-up, catalyst-free conditions and pure products in good to excellent yields.
引用
收藏
页码:825 / 832
页数:8
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