Pediatric deep venous thrombosis

被引:20
作者
Audu, Christopher O. [1 ]
Wakefield, Thomas W. [1 ]
Coleman, Dawn M. [1 ]
机构
[1] Univ Michigan, Dept Surg, Vasc Surg Sect, Michigan Med, Ann Arbor, MI 48109 USA
关键词
Pediatric; DVT; Clot; Thromboembolism; TISSUE-PLASMINOGEN ACTIVATOR; VEIN THROMBOSIS; POSTTHROMBOTIC SYNDROME; RISK-FACTORS; ENDOVASCULAR THROMBOLYSIS; INTRAVASCULAR THROMBOSIS; PROSPECTIVE COHORT; WARFARIN THERAPY; CHILDREN; THROMBOEMBOLISM;
D O I
10.1016/j.jvsv.2018.12.012
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Deep venous thrombosis (DVT) in the pediatric population is rare, occurring in about 10 to 14 out of 10,000 pediatric admissions annually, but with serious consequences such as pulmonary embolism and/or post-thrombotic syndrome. There is a dearth of surgical literature regarding this entity, its pathophysiology, its treatment and its long-term sequelae. Methods: An extensive search of available surgical and medical literature in Medline, PubMed was obtained by searching terms synonymous with pediatric DVT. Case reports and opinion articles were excluded. Ongoing clinical trials were culled from clinicaltrial.gov by searching for pediatric DVT studies. Institutional guidelines, where available, were included in this summary. Results: We provide a clinically relevant summary with the aims of improving prevention, early identification and treatment of pediatric DVT. Conclusions: Although rare and frequently with subtle presentations, pediatric DVT can be serious. Early identification and treatment can be instrumental in limiting sequelae and in improving outcomes for these patients.
引用
收藏
页码:452 / 462
页数:11
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