N-Terminal Type III Secretion Signal of Enteropathogenic Escherichia coli Translocator Proteins

被引：30
作者：
Munera, Diana [1 ]
Crepin, Valerie F. [1 ]
Marches, Olivier [1 ]
Frankel, Gad [1 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Ctr Mol Microbiol & Infect, Div Cell & Mol Biol, London SW7 2AZ, England
来源：
JOURNAL OF BACTERIOLOGY | 2010年 / 192卷 / 13期
基金：
英国惠康基金;
关键词：
EFFECTORS; CELLS; INJECTISOME; PATHOGENS; O157-H7; TIR;
D O I：
10.1128/JB.00046-10
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We report that the N terminus of the type III secretion system translocator proteins EspB, EspD, and EspA mediate protein secretion and translocation from wild-type enteropathogenic Escherichia coli and hypersecretion from sepL and sepD mutants. EspA containing the translocation signal of Map and Tir containing the secretion signal of EspA are biologically active.
引用
收藏
页码：3534 / 3539
页数：6
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