Dinuclear ruthenium(II) triple-stranded helicates: Luminescent supramolecular cylinders that bind and coil DNA and exhibit activity against cancer cell lines

被引:171
作者
Pascu, Gabriel I. [1 ]
Hotze, Anna C. G. [1 ]
Sanchez-Cano, Carlos [1 ]
Kariuki, Benson M. [1 ]
Hannon, Michael J. [1 ]
机构
[1] Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England
关键词
bioinorganic chemistry; helical structures; metallodrugs; ruthenium; supramolecular chemistry;
D O I
10.1002/anie.200700656
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure presented) A fluorescent supramolecular cylinder binds noncovalently to DNA and shows anticancer activity in cell lines. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:4374 / 4378
页数:5
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