Non-adherence to cardiovascular medications

被引:187
作者
Kolandaivelu, Kumaran [1 ,2 ]
Leiden, Benjamin B. [1 ]
O'Gara, Patrick T. [2 ]
Bhatt, Deepak L. [2 ]
机构
[1] MIT, Inst Med Engn & Sci, Cambridge, MA 02139 USA
[2] Harvard Univ, Brigham & Womens Hosp, Sch Med, Cardiovasc Div,Dept Med, Boston, MA 02115 USA
关键词
Non-adherence; Coronary heart disease; ACUTE CORONARY SYNDROME; LONG-TERM ADHERENCE; ADVERSE DRUG EVENTS; ANTIHYPERTENSIVE MEDICATION; HOSPITAL DISCHARGE; COST-EFFECTIVENESS; BLOOD-PRESSURE; DOUBLE-BLIND; RISK-FACTORS; OUTCOMES;
D O I
10.1093/eurheartj/ehu364
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Despite evidence-based interventions, coronary heart disease (CHD) remains a leading cause of global mortality. As therapies advance, patient non-adherence to established treatments is well recognized. Non-adherence is a powerful confounder of evidence-based practice and can affect daily patient management, resulting in inappropriate therapeutic escalation with greater costs and potential for harm. Moreover, it increases risk for adverse cardiac events, including mortality. Yet, non-adherence is complex, remains difficult to define, and provider ability to identify its presence accurately remains limited. Improved screening tools are needed to detect at-risk patients, enabling appropriate targeting of interventions. Given the rapidly expanding global population with CHD and emerging clinical and cost-benefits of adherence, addressing non-adherence to prescribed therapies is a top priority.
引用
收藏
页码:3267 / 3276
页数:10
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