Non-adherence to cardiovascular medications

被引:183
作者
Kolandaivelu, Kumaran [1 ,2 ]
Leiden, Benjamin B. [1 ]
O'Gara, Patrick T. [2 ]
Bhatt, Deepak L. [2 ]
机构
[1] MIT, Inst Med Engn & Sci, Cambridge, MA 02139 USA
[2] Harvard Univ, Brigham & Womens Hosp, Sch Med, Cardiovasc Div,Dept Med, Boston, MA 02115 USA
关键词
Non-adherence; Coronary heart disease; ACUTE CORONARY SYNDROME; LONG-TERM ADHERENCE; ADVERSE DRUG EVENTS; ANTIHYPERTENSIVE MEDICATION; HOSPITAL DISCHARGE; COST-EFFECTIVENESS; BLOOD-PRESSURE; DOUBLE-BLIND; RISK-FACTORS; OUTCOMES;
D O I
10.1093/eurheartj/ehu364
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Despite evidence-based interventions, coronary heart disease (CHD) remains a leading cause of global mortality. As therapies advance, patient non-adherence to established treatments is well recognized. Non-adherence is a powerful confounder of evidence-based practice and can affect daily patient management, resulting in inappropriate therapeutic escalation with greater costs and potential for harm. Moreover, it increases risk for adverse cardiac events, including mortality. Yet, non-adherence is complex, remains difficult to define, and provider ability to identify its presence accurately remains limited. Improved screening tools are needed to detect at-risk patients, enabling appropriate targeting of interventions. Given the rapidly expanding global population with CHD and emerging clinical and cost-benefits of adherence, addressing non-adherence to prescribed therapies is a top priority.
引用
收藏
页码:3267 / 3276
页数:10
相关论文
共 50 条
[21]   Initial non-adherence to antihypertensive medications in the United States: a systematic literature review [J].
Cooke, Catherine E. ;
Xing, Shan ;
Gale, Stormi E. ;
Peters, Sadie .
JOURNAL OF HUMAN HYPERTENSION, 2022, 36 (01) :3-13
[22]   Prevalence of Non-Adherence to Immunosuppressive Medications in Kidney Transplant Recipients: Barriers and Predictors [J].
Taj, Shahd M. ;
Baghaffar, Hajer ;
Alnajjar, Duha Khaled ;
Almashabi, Nahed Khalid ;
Ismail, Sherine .
ANNALS OF TRANSPLANTATION, 2021, 26
[23]   Evaluation and implementation of behavioral and educational tools that improves the patients' intentional and unintentional non-adherence to cardiovascular medications in family medicine clinics [J].
Shehab, Abdulla ;
Elnour, Asim Ahmed ;
Al Swaidi, Shirina ;
Bhagavathula, Akshaya Srikanth ;
Hamad, Farah ;
Shehab, Omar ;
AbuMandil, Mahmoud ;
Abasaeed, AboBakr ;
Dahab, Ahmed ;
Al Kalbani, Naama ;
Abdulla, Rouda ;
Asim, Sahar ;
Erkekoglu, Pinar ;
Al Nuaimi, Saif ;
Al Suwaidi, Aaesha .
SAUDI PHARMACEUTICAL JOURNAL, 2016, 24 (02) :182-188
[24]   Non-adherence to statin therapy: a major challenge for preventive cardiology [J].
Bates, T. R. ;
Connaughton, V. M. ;
Watts, G. F. .
EXPERT OPINION ON PHARMACOTHERAPY, 2009, 10 (18) :2973-2985
[25]   Identifying determinants of cardiovascular medication non-adherence to develop individualised interventions [J].
Bakker, Marie de ;
Kimenai, Dorien M. .
HEART, 2025,
[26]   Non-adherence to anti-osteoporotic medications in Taiwan: physician specialty makes a difference [J].
Shan-Fu Yu ;
Tsong-Shing Yang ;
Wen-Chan Chiu ;
Chung-Yuan Hsu ;
Ching-Lan Chou ;
Yu-Jih Su ;
Han-Ming Lai ;
Ying-Chou Chen ;
Chung-Jen Chen ;
Tien-Tsai Cheng .
Journal of Bone and Mineral Metabolism, 2013, 31 :351-359
[27]   Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost [J].
Hanine Abbas ;
Souheil Hallit ;
Mazen Kurdi ;
Rita Karam .
BMC Cardiovascular Disorders, 22
[28]   Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost [J].
Abbas, Hanine ;
Hallit, Souheil ;
Kurdi, Mazen ;
Karam, Rita .
BMC CARDIOVASCULAR DISORDERS, 2022, 22 (01)
[29]   Non-adherence to anti-osteoporotic medications in Taiwan: physician specialty makes a difference [J].
Yu, Shan-Fu ;
Yang, Tsong-Shing ;
Chiu, Wen-Chan ;
Hsu, Chung-Yuan ;
Chou, Ching-Lan ;
Su, Yu-Jih ;
Lai, Han-Ming ;
Chen, Ying-Chou ;
Chen, Chung-Jen ;
Cheng, Tien-Tsai .
JOURNAL OF BONE AND MINERAL METABOLISM, 2013, 31 (03) :351-359
[30]   INTENTIONAL NON-ADHERENCE TO MEDICATIONS IN THE ELDERLY - RESULTS FROM A PILOT STUDY (WARSAW, POLAND) [J].
Dworakowska, Anna Maria ;
Czepielewska, Edyta ;
Andrulonis, Natalia ;
Lisowska, Agnieszka ;
Kozlowska-Wojciechowska, Malgorzata .
ACTA POLONIAE PHARMACEUTICA, 2021, 78 (06) :863-867