Concepts and relevance of genome-wide association studies

被引：23
|
作者：
Scherer, Andreas [1 ]
Christensen, G. Bryce [1 ]
机构：
[1] Golden Helix Inc, Bozeman, MT USA
来源：
SCIENCE PROGRESS | 2016年 / 99卷 / 01期
关键词：
MODEL; GWAS;
D O I：
10.3184/003685016X14558068452913
中图分类号：
G40 [教育学];
学科分类号：
040101 ; 120403 ;
摘要：
Genome-wide association study (GWAS) technology has been a primary method for identifying the genes responsible for diseases and other traits for the past 10 years. Over 2,000 human GWAS reports now appear in the scientific journals. The technology is continuing to improve, and has recently become accessible to researchers studying a wide variety of animals, plants and model organisms. Here, we present an overview of GWAS concepts: the underlying biology, the origins of the method, and the primary components of a GWAS experiment.
引用
收藏
页码：59 / 67
页数：9
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