The synthesis and antioxidant activity of azole derivatives of hemin

被引：0

作者：

Rozhkova, EA

Lysko, AI

Kuleshov, KV

Evstigneeva, RP

机构：

[1] Lomonosov State Acad Fine Chem Technol, Moscow 117571, Russia

[2] Russian Acad Med Sci, Pharmacol Res Inst, Moscow 125315, Russia

来源：

BIOORGANICHESKAYA KHIMIYA | 2000年 / 26卷 / 06期

关键词：

hemin; azoles; synthesis; antioxidant activity; lipid peroxidation; liver homogenates;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

New derivatives of proto- and deuterohemin IX containing tri- and tetrazole rings were synthesized and characterized. A pronounced antioxidant activity was found for these compounds in the Fe(II)/ascorbate-dependent system of lipid peroxidation in murine liver homogenates.

引用

页码：466 / 470

页数：5