Treating Obesity? It's in the Bag!

被引：5
作者：
Coll, Anthony P. [1 ]
机构：
[1] Univ Cambridge, Addenbrookes Hosp, Inst Metab Sci, Metab Res Labs, Cambridge CB2 0QQ, England
来源：
CELL METABOLISM | 2010年 / 11卷 / 02期
基金：
英国惠康基金; 英国医学研究理事会;
关键词：
BOMBESIN RECEPTOR SUBTYPE-3; SUBTYPE-3-DEFICIENT MICE;
D O I：
10.1016/j.cmet.2010.01.006
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
BRS-3 is an orphan G protein coupled receptor highly expressed in the brain. Pharmacological studies in this issue (Guan et al., 2010) further support a role for this receptor in energy homeostasis and show that the BRS-3 agonist Bag-1 effectively causes weight loss by decreasing food intake and increasing metabolic rate.
引用
收藏
页码：95 / 96
页数：2
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