Encapsulated follicular variant of papillary thyroid carcinoma/noninvasive follicular thyroid neoplasm with papillary-like nuclear features with Spindle Cell Metaplasia: Case report and review of literature

被引:7
作者
Al Rasheed, Mohamed Rizwan Haroon [1 ]
Acosta, Andres [1 ]
Tarjan, Gabor [2 ]
机构
[1] Univ Illinois, Dept Pathol, 840 S Wood St,Suite 130 CSN, Chicago, IL 60612 USA
[2] John H Stroger Jr Hosp Cook Cty, Dept Pathol, Chicago, IL USA
关键词
Spindled lesion; HBME-1; Endocrine; Follicular neoplasm; NIFTP; EFVPTC; FINE-NEEDLE-ASPIRATION; SYNOVIAL SARCOMA; CARCINOMA; ADENOMA; TUMOR; PATHOLOGY; GLAND; DIAGNOSIS; ENTITY; FOCI;
D O I
10.1016/j.prp.2016.12.026
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Spindle cell lesions of the thyroid are rare overall, and span a wide clinical spectrum that ranges from spindle cell metaplasia (SCM1) to anaplastic carcinoma. Their differentiation is only seldom straightforward, and usually requires the integration of the clinical, histological and immunohistochemical data. Only a handful of publications have described cases of SCM in the thyroid and we add to that literature by reporting a unique case of encapsulated follicular variant of papillary thyroid carcinoma/noninvasive follicular thyroid neoplasm with papillary-like nuclear features with SCM. In addition, we review the literature on the relationship between SCM and different thyroid lesions, summarizing the morphological and immunohistochemical features that aid in its differentiation from more aggressive spindle cell proliferations. (C) 2017 Elsevier GmbH. All rights reserved.
引用
收藏
页码:416 / 421
页数:6
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