Synthesis of New Triazole and Oxadiazole Derivatives of Quinazolin-4(3H)-one and Their Antimicrobial Activity

被引：9
|
作者：
Vani, Kotla Veena [1 ]
Ramesh, Garlapati [1 ]
Rao, Chunduri Venkata [1 ]
机构：
[1] Sri Venkateswara Univ, Dept Chem, Tirupati 517502, Andhra Pradesh, India
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2016年 / 53卷 / 03期
关键词：
QUINAZOLINE DERIVATIVES; ANTIINFLAMMATORY EVALUATION; ANTIBACTERIAL ACTIVITY; TERMINAL ALKYNES; AGENTS; AZIDES;
D O I：
10.1002/jhet.2353
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of new triazole derivatives of quinazolin-4(3H)-one and new oxadiazole derivatives of quinazolin-4(3H)-one were synthesized. The newly synthesized compounds were characterized by IR, H-1 NMR, C-13 NMR and mass spectral data. All the newly synthesized compounds were screened for antibacterial activity against Staphylococcus aureus, Bacillus subtilis (gram-positive bacteria), Escherichia coli, Pseudomonas aeruginosa (gram-negative bacteria), and antifungal activity was carried out against Candida albicans and Aspergillus niger.
引用
收藏
页码：719 / 726
页数：8
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