A guiding map for inflammation

被引：587

作者：

Netea, Mihai G. ^{[1
,2
,3
]}

Balkwill, Frances ^{[4
]}

Chonchol, Michel ^{[5
]}

Cominelli, Fabio ^{[6
]}

Donath, Marc Y. ^{[7
]}

Giamarellos-Bourboulis, Evangelos J. ^{[8
]}

Golenbock, Douglas ^{[9
]}

Gresnigt, Mark S. ^{[1
,2
]}

Heneka, Michael T. ^{[10
,11
]}

Hoffman, Hal M. ^{[12
,13
]}

Hotchkiss, Richard ^{[14
]}

Joosten, Leo A. B. ^{[1
,2
,15
]}

Kastner, Daniel L. ^{[16
]}

Korte, Martin ^{[17
,18
]}

Latz, Eicke ^{[9
,11
,19
]}

Libby, Peter ^{[20
,21
]}

Mandrup-Poulsen, Thomas ^{[22
]}

Mantovani, Alberto ^{[23
]}

Mills, Kingston H. G. ^{[24
]}

Nowak, Kristen L. ^{[5
]}

O'Neill, Luke A. ^{[24
]}

Pickkers, Peter ^{[25
]}

van der Poll, Tom ^{[26
]}

Ridker, Paul M. ^{[21
,27
,28
]}

Schalkwijk, Joost ^{[29
]}

Schwartz, David A. ^{[30
]}

Siegmund, Britta ^{[31
]}

Steer, Clifford J. ^{[32
,33
]}

Tilg, Herbert ^{[34
]}

van der Meer, Jos W. M. ^{[1
,2
]}

van de Veerdonk, Frank L. ^{[1
,2
]}

Dinarello, Charles A. ^{[1
,2
,35
]}

机构：

[1] Radboud Univ Nijmegen, Med Ctr, Dept Internal Med, Nijmegen, Netherlands

[2] Radboud Univ Nijmegen, Med Ctr, Radboud Ctr Infect Dis, Nijmegen, Netherlands

[3] Craiova Univ Med & Pharm, Human Genom Lab, Craiova, Romania

[4] Queen Mary Univ London, Barts Canc Inst, London, England

[5] Univ Colorado, Div Renal Dis & Hypertens, Aurora, CO USA

[6] Case Western Reserve Univ, Digest Hlth Res Inst, Cleveland, OH 44106 USA

[7] Univ Basel, Univ Hosp, Clin Endocrinol Diabet & Metab, Basel, Switzerland

[8] Univ Athens, Med Sch, Dept Internal Med 4, Athens, Greece

[9] Univ Massachusetts, Sch Med, Div Infect Dis & Immunol, Worcester, MA USA

[10] Univ Bonn, Dept Neurodegenerat Dis & Gerontopsychiat Neurol, Bonn, Germany

[11] German Ctr Neurodegenerat Dis DZNE, Bonn, Germany

[12] Univ Calif San Diego, Div Pediat Allergy Immunol & Rheumatol, San Diego, CA 92103 USA

[13] Univ Calif San Diego, Rady Childrens Hosp San Diego, San Diego, CA 92103 USA

[14] Washington Univ, Sch Med, Dept Anesthesiol Med & Surg, St Louis, MO USA

[15] Iuliu Hatieganu Univ Med & Pharm, Dept Med Genet, Cluj Napoca, Romania

[16] US Natl Inst Hlth, Inflammatory Dis Sect, Metab Cardiovasc & Inflammatory Dis Genom Branch, NHGRI, Bethesda, MD USA

[17] TU Braunschweig, Zool Inst, Braunschweig, Germany

[18] AG NIND, HZI, Braunschweig, Germany

[19] Univ Bonn, Univ Hosp Bonn, Inst Innate Immun, Bonn, Germany

[20] Brigham & Womens Hosp, Dept Med, Cardiovasc Div, 75 Francis St, Boston, MA 02115 USA

[21] Harvard Med Sch, Boston, MA USA

[22] Univ Copenhagen, Dept Biomed Sci, Copenhagen, Denmark

[23] Humanitas Univ, Humanitas Clin Res Ctr, Milan, Italy

[24] Trinity Coll Dublin, Trinity Biomed Sci Inst, Sch Biochem & Immunol, Dublin, Ireland

[25] Radboud Univ Nijmegen, Med Ctr, Dept Intens Care Med, Nijmegen, Netherlands

[26] Univ Amsterdam, Acad Med Ctr, Div Infect Dis, Ctr Expt & Mol Med, Amsterdam, Netherlands

[27] Brigham & Womens Hosp, Ctr Cardiovasc Dis Prevent, 75 Francis St, Boston, MA 02115 USA

[28] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Boston, MA USA

[29] Radboud Univ Nijmegen, Med Ctr, Dept Dermatol, Nijmegen, Netherlands

[30] Univ Colorado, Dept Med, Div Pulm Sci & Crit Care Med, Aurora, CO USA

[31] Charite Univ Med Berlin, Rheumatol, Dept Med, Gastroenterol,Infect Dis, Berlin, Germany

[32] Univ Minnesota, Sch Med, Dept Med, Minneapolis, MN 55455 USA

[33] Univ Minnesota, Sch Med, Dept Genet Cell Biol & Dev, Minneapolis, MN 55455 USA

[34] Med Univ Innsbruck, Dept Internal Med Gastroenterol Hepatol & Endocri, Innsbruck, Austria

[35] Univ Colorado Denver, Dept Med, Aurora, CO USA

来源：

NATURE IMMUNOLOGY | 2017年 / 18卷 / 08期

基金：

美国国家卫生研究院; 爱尔兰科学基金会; 欧盟地平线“2020”;

关键词：

INNATE IMMUNITY; DOUBLE-BLIND; SEPSIS; RECEPTORS; CELLS; RECOGNITION; INDUCTION; CYTOKINES; ARTHRITIS; INSIGHTS;

D O I：

10.1038/ni.3790

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Biologists, physicians and immunologists have contributed to the understanding of the cellular participants and biological pathways involved in inflammation. Here, we provide a general guide to the cellular and humoral contributors to inflammation as well as to the pathways that characterize inflammation in specific organs and tissues.

引用

页码：826 / 831

页数：6

共 54 条

[21] Immunopathogenesis of Rheumatoid Arthritis [J].