Acute reversible myocardial depression associated with sepsis

被引:3
作者
Kontani, M
Izumiya, Y
Shimizu, M
Yasuma, K
Inada, A
Ohta, H
Ikeda, T
机构
[1] Tsuruga Municipal Hosp, Dept Cardiol, Fukui 9148502, Japan
[2] Tsuruga Municipal Hosp, Dept Internal Med, Fukui, Japan
[3] Tsuruga Municipal Hosp, Dept Gastroenterol, Fukui, Japan
关键词
sepsis; left ventricular failure; proinflammatory cytokines;
D O I
10.2169/internalmedicine.42.60
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 30-year-old man was admitted to our hospital for left lobar pneumonia with septic shock. Acute left-sided heart failure became evident as sepsis developed. Echocardiography revealed diffuse severe hypokinesis of the left ventricle (LV) and a pulmonary artery catheter showed Forrester subset II hemodynamics. Along with amelioration of sepsis and decrease of the serum concentrations of tumor necrosis factor-a and interleukin-6, LV hypokinesis improved. It is suggested that the patient's heart failure may have been due to functional depression of myocardial contractility resulting from a direct effect of the cytokines towards the cardiomyocytes, the so-called "septic myocardial depression".
引用
收藏
页码:60 / 65
页数:6
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