How do you treat bleeding disorders with desmopressin?

被引：43

作者：

Oezgoenenel, Buelent ^{[1
]}

Rajpurkar, Madhvi ^{[1
]}

Lusher, Jeanne M. ^{[1
]}

机构：

[1] Wayne State Univ, Childrens Hosp Michigan, Div Hematol Oncol, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA

来源：

POSTGRADUATE MEDICAL JOURNAL | 2007年 / 83卷 / 977期

关键词：

D O I：

10.1136/pgmj.2006.052118

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Desmopressin is an analog of vasopressin that exerts a substantial haemostatic effect by inducing the release of von Willebrand factor from its storage sites in endothelial cells. It has proved useful in treating or preventing bleeding episodes in patients with von Willebrand disease, haemophilia A and platelet function defects. Its efficacy in achieving a satisfactory level of haemostasis has reduced the use of blood products to treat bleeding episodes. Clinicians need to become familiar with the use of this drug that has become a home medication for many patients with inherited bleeding disorders.

引用

页码：1159 / 1163

页数：5

共 26 条

[1] Oral contraceptives and DDAVP nasal spray: Patterns of use in managing vWD-associated menorrhagia - A single-institution study [J].