Structure, functions, and biosynthesis of glycoconjugates of Leishmania spp. cell surface

被引:28
作者
Novozhilova, N. M. [1 ]
Bovin, N. V. [1 ]
机构
[1] Russian Acad Sci, Shemyakin & Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia
关键词
D-arabinopyranose; Leishmania; glycosylphosphatidylinositol; lipophosphoglycan; glycosylinositol phospholipids; proteophosphoglycan; PROTEIN-KINASE-C; PROTOZOAN PARASITE LEISHMANIA; TARGETED GENE DELETION; NITRIC-OXIDE SYNTHASE; GLYCOSYLATED-PHOSPHATIDYLINOSITOLS; MEXICANA AMASTIGOTES; SIGNAL-TRANSDUCTION; TRYPANOSOMA-BRUCEI; D-ARABINOPYRANOSE; LIPOPHOSPHOGLYCAN;
D O I
10.1134/S0006297910060027
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cell surface of leishmaniasis causal agent, a parasitic member of Protozoa of Leishmania genus, is covered by thick glycocalix consisting of various phosphatidylinositol-anchored molecules. This review deals with the structure and biosynthesis of the main phosphoglycans and glycoproteins of Leishmania cell surface, many of which incorporate the rare natural D-arabinopyranose, and the problem concerning the involvement of these molecules in support of Leishmania survival during their intricate life cycle is discussed.
引用
收藏
页码:686 / 694
页数:9
相关论文
共 50 条
[31]   Clinical, diagnostic and epidemiological implications of Hepatozoon spp., Babesia spp. and Leishmania infantum infection in cats and dogs in a Mediterranean periurban setting [J].
Ortuno, Maria ;
Bernal, Ana ;
Nachum-Biala, Yaarit ;
Munoz, Clara ;
Risueno, Jose ;
Ortiz, Juana ;
Baneth, Gad ;
Berriatua, Eduardo .
PARASITOLOGY RESEARCH, 2023, 122 (01) :35-47
[32]   The Widespread Anti-Protozoal Action of HIV Aspartic Peptidase Inhibitors: Focus on Plasmodium spp., Leishmania spp. and Trypanosoma cruzi [J].
Branquinha, Marta H. ;
Sangenito, Leandro S. ;
Sodre, Catia L. ;
Kneipp, Lucimar F. ;
d'Avila-Levy, Claudia M. ;
Santos, Andre L. S. .
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2017, 17 (11) :1303-1317
[33]   Seroprevalence and molecular detection of Leishmania spp. in cats of West Aegean Region, Turkey [J].
Aksulu, Ayca ;
Bilgic, Huseyin Bilgin ;
Karagenc, Tulin ;
Bakirci, Serkan .
VETERINARY PARASITOLOGY- REGIONAL STUDIES AND REPORTS, 2021, 24
[34]   Antibodies to Toxoplasma gondii and Leishmania spp. in domestic cats from Luanda, Angola [J].
Lopes, Ana Patricia ;
Oliveira, Ana Cristina ;
Granada, Sara ;
Rodrigues, Filipa T. ;
Papadopoulos, Elias ;
Schallig, Henk ;
Dubey, Jitender P. ;
Cardoso, Luis .
VETERINARY PARASITOLOGY, 2017, 239 :15-18
[35]   Development and evaluation of zinc phthalocyanine nanoemulsions for use in photodynamic therapy for Leishmania spp. [J].
de Oliveira de Siqueira, Luciana Betzler ;
Cardoso, Veronica da Silva ;
Rodrigues, Igor Almeida ;
Vazquez-Villa, Ana Lucia ;
dos Santos, Elisabete Pereira ;
Leal Ribeiro Guimaraes, Bruno da Costa ;
Cerqueira Coutinho, Cristal dos Santos ;
Vermelho, Alane Beatriz ;
Ricci Junior, Eduardo .
NANOTECHNOLOGY, 2017, 28 (06)
[36]   Chiropterans as a potential hosts of Leishmania spp. in endemic areas for leishmaniasis in northeastern Brazil [J].
Siqueira Matias Ramos, Luis Gustavo ;
Costa, Valeria Almeida ;
Louzeiro, Nayara Mendes ;
Alves Carvalho, Clauberth Cesar ;
Seabra Nogueira, Rita de Maria ;
Speranca, Marcia Aparecida ;
Cabral, Aline Diniz ;
Costa, Francisco Borges ;
Barros, Maria Claudene ;
Fraga, Elmary da Costa ;
Marcili, Arlei ;
da Costa, Andrea Pereira .
ZOONOSES AND PUBLIC HEALTH, 2022, 69 (08) :987-992
[37]   Evaluation of 4 polymerase chain reaction protocols for cultured Leishmania spp. typing [J].
Rocha, Marcele Neves ;
Margonari, Carina ;
Presot, Ivanete Milagres ;
Soares, Rodrigo Pedro .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2010, 68 (04) :401-409
[38]   Dynamics of sterol synthesis during development of Leishmania spp. parasites to their virulent form [J].
Yao, Chaoqun ;
Wilson, Mary E. .
PARASITES & VECTORS, 2016, 9 :1-12
[39]   Detection of Leishmania spp. in Chronic Dermatitis: Retrospective Study in Exposed Horse Populations [J].
Gazzonis, Alessia Libera ;
Morganti, Giulia ;
Porcellato, Ilaria ;
Roccabianca, Paola ;
Avallone, Giancarlo ;
Gavaudan, Stefano ;
Canonico, Cristina ;
Rigamonti, Giulia ;
Brachelente, Chiara ;
Veronesi, Fabrizia .
PATHOGENS, 2022, 11 (06)
[40]   Tracking of Leishmania spp. in Iranian phlebotominae, distribution and biodiversity in Jarqavieh county, central Iran [J].
Haddadnia, Mehdi ;
Esmaeilifallah, Mahsa ;
Badiezadeh, Parisima ;
Abtahi, Seyed Mohammad .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH, 2025,