LONGITUDINAL MOVEMENT OF THE COMMON CAROTID ARTERY WALL: NEW INFORMATION ON CARDIOVASCULAR AGING

被引:21
作者
Cinthio, Magnus [1 ]
Albinsson, John [1 ]
Erlov, Tobias [1 ]
Bjarnegard, Niclas [2 ]
Lanne, Toste [2 ]
Ahlgren, Asa Ryden [3 ,4 ]
机构
[1] Lund Univ, Fac Engn, Dept Biomed Engn, Lund, Sweden
[2] Univ Linkoping, Dept Med & Hlth Sci, Linkoping, Sweden
[3] Lund Univ, Dept Translat Med, Lund, Sweden
[4] Lund Univ, Skane Univ Hosp, Dept Med Imaging & Physiol, Malmo, Sweden
基金
瑞典研究理事会;
关键词
Aging; Ultrasound; Biomarkers; Physiology; Hemodynamics; Clinical studies; Atherosclerosis; Vascular disease; INTIMA-MEDIA THICKNESS; SHEAR STRAIN; DISPLACEMENT; ULTRASOUND; DIAMETER; DISEASE; MOTION; AGE;
D O I
10.1016/j.ultrasmedbio.2018.06.001
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Putative changes in the multiphasic pattern of longitudinal movement of the common carotid artery wall in the normal aging process are unknown. The aim of this study was to explore the phases, and resulting patterns, of the longitudinal movement of the intima-media complex of the human common carotid artery with respect to age and gender. One hundred thirty-five healthy non-smoking patients of different ages were investigated using in-house-developed ultrasound methods. The patterns of longitudinal movement seen in middle-aged and older patients were markedly different from those commonly seen in young patients, including the appearance of two additional phases of motion and, thus, new complex patterns. The displacement and maximum velocity of one of the phases, occurring at the time of aortic valve closure, increased quadratically with age in both men and women. (C) 2018 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
引用
收藏
页码:2283 / 2295
页数:13
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