Questionnaire-based diagnosis of hidradenitis suppurativa: specificity, sensitivity and positive predictive value of specific diagnostic questions

被引:67
作者
Esmann, S. [1 ]
Dufour, D. N. [1 ]
Jemec, G. B. E. [1 ]
机构
[1] Univ Copenhagen, Dept Dermatol, Roskilde Hosp, Fac Hlth Sci, DK-4000 Roskilde, Denmark
关键词
diagnosis; epidemiology; hidradenitis suppurativa; questionnaires; skin disease; PREVALENCE;
D O I
10.1111/j.1365-2133.2010.09773.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
P>Background Estimates of the prevalence of hidradenitis suppurativa (HS) range from 0 center dot 33% to 4%. Further epidemiological data are therefore needed. Because of the hidden nature of the disease, physical screening may be cumbersome and questionnaire-based screening may be more appropriate. Objectives To establish the sensitivity (SE), specificity (SP) and positive predictive value (PPV) of simple diagnostic questions used in HS. Methods Potential diagnostic questions regarding HS were identified and sent to 85 patients with HS and to an age- and sex-matched control group randomly selected among outpatients not being treated for HS. All respondents were recruited in the Department of Dermatology in Roskilde Hospital. Results In total, 74 of 85 patients with HS (87%) returned the questionnaire (61 women and 13 men). Of these, 72 reported repeated outbreaks of painful nodules or boils in locations typical for HS compared with 13 patients in the control group. The SE ranged from 0 center dot 92 to 0 center dot 97, the SP from 0 center dot 82 to 0 center dot 86 and the PPV from 0 center dot 85 to 0 center dot 89. Boils appeared significantly more often in patients with HS, who also reported significantly greater suffering from their lesions. Conclusions The high diagnostic power suggests that all the questions are potentially useful. The clear symptomatology of HS may be a key factor. It is suggested that further improvement may be achieved by adding definitions of pimples, nodules or boils to future questionnaires. Similarly, adding the possibility to indicate uncommon locations, duration and quality-of-life impairment may benefit the diagnostic power.
引用
收藏
页码:102 / 106
页数:5
相关论文
共 12 条
[1]  
[Anonymous], 2009, 2 INT C HIDR SUPP MA
[2]   Clinical characteristics of a series of 302 French patients with hidradenitis suppurativa, with an analysis of factors associated with disease severity [J].
Canoui-Poitrine, Florence ;
Revuz, Jean E. ;
Wolkenstein, Pierre ;
Viallette, Cedric ;
Gabison, Germaine ;
Pouget, Florence ;
Poli, Florence ;
Faye, Ousmane ;
Bastuji-Garin, Sylvie .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2009, 61 (01) :51-57
[3]   The validity of a questionnaire-based epidemiological study of occupational dermatosis [J].
Carstensen, Ole ;
Rasmussen, Kurt ;
Ponten, Ann ;
Gruvberger, Birgitta ;
Isaksson, Marlene ;
Bruze, Magnus .
CONTACT DERMATITIS, 2006, 55 (05) :295-300
[4]  
Hurley H.J., 1989, Dermatologic surgery, principles and practice
[5]   The prevalence of hidradenitis suppurativa and its potential precursor lesions [J].
Jemec, GBE ;
Heidenheim, M ;
Nielsen, NH .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1996, 35 (02) :191-194
[6]   Hidradenitis suppurativa [J].
Jemec, GBE .
JOURNAL OF CUTANEOUS MEDICINE AND SURGERY, 2003, 7 (01) :47-56
[8]  
Naldi L., 2006, Hidradenitis suppurativa, P58, DOI 10.1007/978-3-540-33101-8_8
[9]   Hidradenitis suppurativa [J].
Revuz, J. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2009, 23 (09) :985-998
[10]   Prevalence and factors associated with hidradenitis suppurativa: Results from two case-control studies [J].
Revuz, Jean E. ;
Canoui-Poitrine, Florence ;
Wolkenstein, Pierre ;
Viallette, Cedric ;
Gabison, Germaine ;
Pouget, Florence ;
Poli, Florence ;
Faye, Ousmane ;
Roujeau, Jean Claude ;
Bonnelye, Genevieve ;
Grob, Jean Jacques ;
Bastuji-Garin, Sylvie .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2008, 59 (04) :596-601