A double-blind placebo-controlled study to assess the efficacy of a compound analgesic to prevent postoperative pain following oral surgery

被引:3
作者
Sandhu, S
Rood, JP
机构
[1] Dept. Oral and Maxillofacial Surg., Turner Dental School, Manchester M15 6FH, Higher Cambridge Street
关键词
D O I
10.1038/sj.bdj.4809081
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
It has been suggested that small doses of opioid drugs given prior to surgery can reduce postoperative pain. This study was designed to compare the effectiveness of a paracetamol/codeine combination and paracetamol alone in preventing the pain following surgical removal of impacted third molar teeth under general anaesthesia. Analysis of the results showed no statistical differences between treatment groups when compared with placebo. We suggest that the opioids may not be the best drugs available to prevent the moderate to severe pain present following some oral surgery procedures.
引用
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页码:335 / 338
页数:4
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