Clinical importance of bacterial translocation

被引:0
作者
de Lorenzo y Mateos, A. Garcia [1 ]
Acosta Escribano, J.
Rodriguez Montes, J. A.
机构
[1] Hosp Univ La Paz, Catedra UAM Abbott Med Crit, Serv Med Intens, Madrid, Spain
[2] Hosp Gen Univ, Serv Med Intens, Alicante, Spain
[3] Hosp Univ La Paz, Serv Cirugia Gen & Digest, Catedrat Cirugia UAM, Madrid, Spain
关键词
bacterial translocation; intestinal permeability;
D O I
暂无
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The gastrointestinal tract is colonized by a huge number of microorganisms that we call intestinal flora. Although the bowel provides a functional barrier between these organisms and the host, bacterial translocation is not an infrequent event in healthy people. However, in critically ill patients, carriers of different morbid entities, bacterial translocation may favor infections and increased morbimortality. There are several proposed mechanisms explaining the etiology, genesis, and ways for this entity, and frequently the results from both in vitro and animal experimental investigations are controversial and difficult to apply to humans. Many diseases have been linked or are implicated in the translocation phenomenon, although studies with insufficient methodology, reduced populations, and conflicting results still leave open questions and others with no logical answer. This problem is also reflected when studying and assessing different therapeutic strategies used as well as on the methods used to detect translocation.
引用
收藏
页码:50 / 55
页数:6
相关论文
共 23 条
[21]  
Wazna Ewa, 2005, Postepy Hig Med Dosw (Online), V59, P267
[22]   Bacterial translocation in the gut [J].
Wiest, R ;
Rath, HC .
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2003, 17 (03) :397-425
[23]  
ZIEGLER TR, 1988, ARCH SURG-CHICAGO, V123, P1313