Inhibition of proliferation in primary human hepatocytes following in vivo AAV-mediated genome editing

被引：0
作者：
Amaya, A. K. [1 ]
Ginn, S. L. [1 ]
Liao, S. H. Y. [1 ]
Zhu, C. [1 ]
Smyth, C. M. [1 ]
Logan, G. J. [1 ]
Lisowski, L. [1 ]
Alexander, I. E. [1 ]
机构：
[1] Childrens Med Res Inst, Westmead, NSW, Australia
来源：
HUMAN GENE THERAPY | 2019年 / 30卷 / 11期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
OR50
引用
收藏
页码：A18 / A18
页数：1
相关论文
共 50 条
  • [21] Factors Impacting Efficacy of AAV-Mediated CRISPR-Based Genome Editing for Treatment of Choroidal Neovascularization
    Chung, Sook Hyun
    Mollhoff, Iris Natalie
    Nguyen, Uyen
    Nguyen, Amy
    Stucka, Natalie
    Tieu, Eric
    Manna, Suman
    Meleppat, Ratheesh Kumar
    Zhang, Pengfei
    Nguyen, Emerald Lovece
    Fong, Jared
    Zawadzki, Robert
    Yiu, Glenn
    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2020, 17 : 409 - 417
  • [22] Single AAV-mediated mutation replacement genome editing in limited number of photoreceptors restores vision in mice
    Koji M. Nishiguchi
    Kosuke Fujita
    Fuyuki Miya
    Shota Katayama
    Toru Nakazawa
    Nature Communications, 11
  • [23] Emerging Issues in AAV-Mediated In Vivo Gene Therapy
    Colella, Pasqualina
    Ronzitti, Giuseppe
    Mingozzi, Federico
    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2018, 8 : 87 - 104
  • [24] Novel AAV-mediated genome editing therapy improves health and survival in a mouse model of methylmalonic acidemia
    Zhang, Shengwen
    Bastille, Amy
    Gordo, Susana
    Ramesh, Nikhil
    Vora, Jenisha
    McCarthy, Elizabeth
    Zhang, Xiaohan
    Frank, Dylan
    Ko, Chih-Wei
    Wu, Carmen
    Walsh, Noel
    Amarwani, Shreya
    Liao, Jing
    Xiong, Qiang
    Drouin, Lauren
    Hebben, Matthias
    Chiang, Kyle
    Chau, B. Nelson
    PLOS ONE, 2022, 17 (09):
  • [25] AAV-MEDIATED, IN VIVO GENE DELIVERY TO THE ROTATOR CUFF
    Sherwin, R. E.
    Mcglinch, E. B.
    Barry, M. A.
    Padilla, C. M. Lopez De
    Montonye, D. R.
    Evans, C. H.
    Atasoy-Zeybek, A.
    EUROPEAN CELLS & MATERIALS, 2023, 46 : 154 - 170
  • [26] SUSTAINED HIGH LEVEL EXPRESSION OF FVII FOLLOWING AAV-MEDIATED GENE DELIVERY IN VIVO
    D'Amico, A.
    Blits, B.
    Van Den Herik, J.
    De Winter, F.
    Kaijen, P.
    Hobo, B.
    Verhaagen, J.
    Mosmuller, D.
    Voorberg, J.
    HAEMOPHILIA, 2023, 29 : 13 - 14
  • [27] Standard screening methods underreport AAV-mediated transduction and gene editing
    Lang, Jonathan F.
    Toulmin, Sushila A.
    Brida, Kasey L.
    Eisenlohr, Laurence C.
    Davidson, Beverly L.
    NATURE COMMUNICATIONS, 2019, 10 (1)
  • [28] Nuclease-free, promoterless recombinant AAV-mediated genome editing restores function of hepatocytes leading to selective advantage and repopulation in mouse models with liver disease
    Zhang, S.
    Bastille, A.
    Ramesh, N.
    McCarthy, E.
    Vora, J.
    Ko, C.
    Wu, C.
    Walsh, N.
    Frank, D.
    Wang, C. C.
    Wang, S.
    Wang, J.
    Freland, L.
    Liao, J.
    Gordo, S.
    Xiong, Q.
    Drouin, L.
    Preston, G.
    Hebben, M.
    Chiang, K.
    Chau, N.
    Nacht, M.
    HUMAN GENE THERAPY, 2021, 32 (19-20) : A16 - A16
  • [29] Standard screening methods underreport AAV-mediated transduction and gene editing
    Jonathan F. Lang
    Sushila A. Toulmin
    Kasey L. Brida
    Laurence C. Eisenlohr
    Beverly L. Davidson
    Nature Communications, 10
  • [30] Impact of liver fibrosis on AAV-mediated gene transfer to mouse hepatocytes
    Ferriero, Rosa
    Bruno, Gemma
    Padula, Agnese
    Pisano, Simone
    Boffa, Iolanda
    Gargaro, Marco
    Imperatore, Teresa
    Battipaglia, Maria
    Vivenzio, Silvia
    Perna, Claudia
    Nusco, Edoardo
    Ferrante, Luigi
    Westhaus, Adrian
    Knight, Maddison
    Manni, Giorgia
    Campione, Severo
    Di Napoli, Evaristo
    Polishchuk, Elena
    Polishchuk, Roman
    Paciello, Orlando
    Brunetti-Pierri, Nicola
    Lisowski, Leszek
    Fallarino, Francesca
    Piccolo, Pasquale
    NATURE COMMUNICATIONS, 2025, 16 (01)
12345