Review: Self-radiolysis of compounds containing tritium and carbon-14

被引：7

作者：

Wolf, Jeremy R. ^{[1
]}

机构：

[1] Eurofins BioPharma Testing, Synth Dept, 7200 E ABC Lane, Columbia, MO 65202 USA

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2021年 / 64卷 / 08期

关键词：

carbon-14; review; stability; tritium; LASER-PULSE PHOTOLYSIS; RADIATION-CHEMISTRY; THERMAL-DECOMPOSITION; RELATIVE-HUMIDITY; ORGANIC-COMPOUNDS; FLASH-PHOTOLYSIS; H/D EXCHANGE; STABILITY; CYCLOHEXANE; THYMIDINE;

D O I：

10.1002/jlcr.3903

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Energy released from beta emission causes molecules that incorporate tritium (H-3) and carbon-14 (C-14) atoms to be less stable than their stable labeled counterparts, thus making radiolabeled compounds prone to self-radiolysis. This literature review examines the stability of organic compounds incorporating H-3 and C-14 atoms and discusses stability of the compound with respect to functional groups within the radiolabeled molecules. The goal of this paper is to serve as a reference for the stability of radiolabeled compounds.

引用

页码：286 / 335

页数：50

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