Hepatitis B prophylaxis: Cost-benefit analysis after liver transplantation

被引:0
|
作者
Golling, M [1 ]
Arnold, JC [1 ]
Rudek, B [1 ]
Theilmann, L [1 ]
Herfarth, C [1 ]
Otto, G [1 ]
机构
[1] Univ Heidelberg, Chirurg Klin, D-69120 Heidelberg, Germany
来源
EFFICIENCY AND ECONOMICS OF CLINICAL CARE AND RESEARCH IN SURGERY | 1997年 / SUPPL卷
关键词
HBV recurrence; hyperimmunoglobulintherapy; costs;
D O I
暂无
中图分类号
R61 [外科手术学];
学科分类号
摘要
HBV recurrence, despite immunoprophylaxis which occurred in 67% of our patients, remains the main problem following liver transplantation for HBV infection. Pretransplant viral replication (HBV-DNA) and probably viral mutation may account to some degree for the failures involved in hyperimmunoglobulin prophylaxis. In order to improve the cost/benefit relationship, only HBV-DNA and HBeAG-negative patients should be selected or preoperatively seroconverted by nucleosides (famciclovir, lamivudine); postoperatively a variable HIG prophylaxis should be administered.
引用
收藏
页码:1048 / 1050
页数:3
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