Force Required to Disassemble Block Copolymer Micelles in Water

被引：13
|
作者：
Yu, Ying [1 ]
Wu, Guanglu [1 ]
Liu, Kai [1 ]
Zhang, Xi [1 ]
机构：
[1] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China
来源：
LANGMUIR | 2010年 / 26卷 / 12期
关键词：
SINGLE-MOLECULE; SPECTROSCOPY REVEALS; MECHANICAL STABILITY; AFM; ADHESION; PROTEINS; POLYMERS; STRENGTH; BOND;
D O I：
10.1021/la101235e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The force required to disassemble block copolymer micelles in water has been directly investigated via atomic force microscopy-based single-molecule force spectroscopy. The force needed to disassemble block copolymer micelles of poly(acrylic acid)-polyfluorene-poly(acrylic acid) in water is found to be 23 pN. The force increases as the stretching velocity increases, indicating that micelle disassembly is a dynamic process. In addition, the disassembly force is sensitive to the properties of the solvents. This study represents the first attempt to employ single-molecule force spectroscopy to directly measure the force needed to disassemble block copolymer micelles in water.
引用
收藏
页码：9183 / 9186
页数：4
相关论文
共 50 条
  • [21] Nanoscale Investigation of Elasticity Changes and Augmented Rigidity of Block Copolymer Micelles Induced by Reversible Core-Cross-Linking
    Wang, Xinyue
    Stihl, Andreas
    Hoeppener, Christiane
    Vitz, Juergen
    Schacher, Felix H.
    Deckert, Volker
    ACS APPLIED MATERIALS & INTERFACES, 2025,
  • [22] Polarizability of DNA Block Copolymer Nanoparticles Observed by Electrostatic Force Microscopy
    Sowwan, Mukhles
    Faroun, Maryam
    Mentovich, Elad
    Ibrahim, Imad
    Haboush, Shayma
    Alemdaroglu, Fikri Emrah
    Kwak, Minseok
    Richter, Shachar
    Herrmann, Andreas
    MACROMOLECULAR RAPID COMMUNICATIONS, 2010, 31 (14) : 1242 - 1246
  • [23] New Design of Thiol-Responsive Degradable Polylactide-Based Block Copolymer Micelles
    Cunningham, Alexander
    Oh, Jung Kwon
    MACROMOLECULAR RAPID COMMUNICATIONS, 2013, 34 (02) : 163 - 168
  • [24] Excipient-free lyophilization of block copolymer micelles for potential lung surfactant therapy applications
    Kim, Seyoung
    Park, Sungwan
    Fesenmeier, Daniel J.
    Won, You-Yeon
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 646
  • [25] Electrogenerated Chemiluminescence of Iridium-Containing ROMP Block Copolymer and Self-Assembled Micelles
    Tefashe, Ushula M.
    Metera, Kimberly L.
    Sleiman, Hanadi F.
    Mauzeroll, Janine
    LANGMUIR, 2013, 29 (41) : 12866 - 12873
  • [26] Control over the structure of ice and water by block copolymer additives
    Mastai, Y
    Rudloff, J
    Cölfen, H
    Antonietti, M
    CHEMPHYSCHEM, 2002, 3 (01) : 119 - 123
  • [27] pH and Ionic Strength Responsive Polyelectrolyte Block Copolymer Micelles Prepared by Ring Opening Metathesis Polymerization
    Stubenrauch, Kurt
    Voets, Ilja
    Fritz-Popovski, Gerhard
    Trimmel, Gregor
    JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2009, 47 (04) : 1178 - 1191
  • [28] Preparation and optimization of biodegradable star-block copolymer micelles for temperature-triggered drug release
    Li, Jianbo
    Leng, Junzhao
    Qu, Yang
    Deng, Li
    Ren, Jie
    MATERIALS LETTERS, 2014, 131 : 5 - 8
  • [29] Inside Block Copolymer Micelles-Tracing Interfacial Influences on Crosslinking Efficiency in Nanoscale Confined Spaces
    Hoeppener, Christiane
    Elter, Johanna K.
    Schacher, Felix H.
    Deckert, Volker
    SMALL, 2023, 19 (20)
  • [30] pH-responsive destabilization and facile bioconjugation of new hydroxyl-terminated block copolymer micelles
    Khorsand, Behnoush
    Oh, Jung Kwon
    JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2013, 51 (07) : 1620 - 1629
12345