Magnetic fractionation and characterization of magnetic nanoparticles for magnetic particle imaging

被引:11
作者
Yoshida, Takashi [1 ]
Nakamura, Takuru [1 ]
Higashi, Oji [1 ]
Enpuku, Keiji [1 ]
机构
[1] Kyushu Univ, Dept Elect Engn, Fukuoka, Fukuoka 8190395, Japan
基金
日本学术振兴会;
关键词
IN-VIVO; FERROFLUID; FLUIDS;
D O I
10.7567/JJAP.57.080302
中图分类号
O59 [应用物理学];
学科分类号
摘要
We performed magnetic fractionation and characterization of Resovist (R) magnetic nanoparticles (MNPs) for use in magnetic particle imaging (MPI). We showed that the core size of the fractionated MNPs can be controlled by adjusting the separation field. We also showed that particles with core size of approximately 27 nm are optimal for MPI applications. To obtain MNPs of an appropriate core size and a narrow size distribution, we performed combined positive and negative fractionation. In the obtained fractionated MNPs, the third harmonic magnetization, which is used as the MPI signal, was 2.75 times as large as that of the original sample. (C) 2018 The Japan Society of Applied Physics
引用
收藏
页数:4
相关论文
共 21 条
[1]   New method for the determination of the particle magnetic moment distribution in a ferrofluid [J].
Berkov, DV ;
Görnert, P ;
Buske, N ;
Gansau, C ;
Mueller, J ;
Giersig, M ;
Neumann, W ;
Su, D .
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2000, 33 (04) :331-337
[2]  
Coffey W.T., 1993, ADV CHEM PHYS, V83, P263, DOI [10.1002/9780470141410.ch5/summary, DOI 10.1002/9780470141410.CH5]
[3]   How the size distribution of magnetic nanoparticles determines their magnetic particle imaging performance [J].
Eberbeck, D. ;
Wiekhorst, F. ;
Wagner, S. ;
Trahms, L. .
APPLIED PHYSICS LETTERS, 2011, 98 (18)
[4]   Empirical expression for DC magnetization curve of immobilized magnetic nanoparticles for use in biomedical applications [J].
Elrefai, Ahmed L. ;
Sasayama, Teruyoshi ;
Yoshida, Takashi ;
Enpuku, Keiji .
AIP ADVANCES, 2018, 8 (05)
[5]   Magnetic Core-Size Distribution of Magnetic Nanoparticles Estimated From Magnetization, AC Susceptibility, and Relaxation Measurements [J].
Elrefai, Ahmed L. ;
Sasayama, Teruyoshi ;
Yoshida, Takashi ;
Enpuku, Keiji .
IEEE TRANSACTIONS ON MAGNETICS, 2017, 53 (11)
[6]   Estimation of magnetic moment and anisotropy energy of magnetic markers for biosensing application [J].
Enpuku, K. ;
Sasayama, T. ;
Yoshida, T. .
JOURNAL OF APPLIED PHYSICS, 2016, 119 (18)
[7]   Tomographic imaging using the nonlinear response of magnetic particles [J].
Gleich, B ;
Weizenecker, R .
NATURE, 2005, 435 (7046) :1214-1217
[8]  
Jordan A, 2003, J NANOPART RES, V5, P597, DOI 10.1023/B:NAN0.0000006155.67098.44
[9]   How Hydrodynamic Fractionation Influences MPI Performance of Resovist [J].
Loewa, Norbert ;
Knappe, Patrick ;
Wiekhorst, Frank ;
Eberbeck, Dietmar ;
Thuenemann, Andreas F. ;
Trahms, Lutz .
IEEE TRANSACTIONS ON MAGNETICS, 2015, 51 (02)
[10]   Hydrodynamic and magnetic fractionation of superparamagnetic nanoparticles for magnetic particle imaging [J].
Loewa, Norbert ;
Knappe, Patrick ;
Wiekhorst, Frank ;
Eberbeck, Dietmar ;
Thuenemann, Andreas F. ;
Trahms, Lutz .
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2015, 380 :266-270