Staphylococcus aureus host cell invasion and post-invasion events

被引：124

作者：

Sinha, Bhanu ^{[1
]}

Fraunholz, Martin ^{[2
]}

机构：

[1] Univ Wurzburg, Inst Hyg & Microbiol, D-97080 Wurzburg, Germany

[2] Ernst Moritz Arndt Univ Greifswald, FunGene Competence Ctr Funct Genom, D-17487 Greifswald, Germany

来源：

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY | 2010年 / 300卷 / 2-3期

关键词：

Staphylococcus aureus; Invasion; Phagosomal escape; Intracellular persistence; Host cell death; alpha-Toxin; FIBRONECTIN-BINDING PROTEINS; HUMAN ENDOTHELIAL-CELLS; EPITHELIAL-CELLS; ALPHA-TOXIN; VIRULENCE FACTORS; HUMAN KERATINOCYTES; NASAL COLONIZATION; HUMAN NEUTROPHILS; TEICHOIC-ACIDS; DEATH PATHWAY;

D O I：

10.1016/j.ijmm.2009.08.019

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Staphylococcus aureus is now recognized as a facultative intracellular pathogen. The aim of this review is to discuss novel data regarding the invasion mechanism and post-invasion events with a focus on the fate of the infected phagosome in non-professional phagocytes and the role of S. aureus alpha-toxin. (C) 2009 Elsevier GmbH. All rights reserved.

引用

页码：170 / 175

页数：6

共 55 条

[1] α-toxin is a mediator of Staphylococcus aureus-induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signaling [J].

Bantel, H ;

Sinha, B ;

Domschke, W ;

Peters, G ;

Schulze-Osthoff, K ;

Jänicke, RU .

JOURNAL OF CELL BIOLOGY, 2001, 155 (04) :637-647

[2] Intracellular Staphylococcus aureus escapes the endosome and induces apoptosis in epithelial cells [J].

Bayles, KW ;

Wesson, CA ;

Liou, LE ;

Fox, LK ;

Bohach, GA ;

Trumble, WR .

INFECTION AND IMMUNITY, 1998, 66 (01) :336-342

[3] Global analysis of community-associated methicillin-resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection [J].

Burlak, Christopher ;

Hammer, Carl H. ;

Robinson, Mary-Ann ;

Whitney, Adeline R. ;

McGavin, Martin J. ;

Kreiswirth, Barry N. ;

DeLeo, Frank R. .

CELLULAR MICROBIOLOGY, 2007, 9 (05) :1172-1190

[4] Staphylococcus aureus interactions with the endothelium -: The role of bacterial "Secretable Expanded Repertoire Adhesive Molecules" (SERAM) in disturbing host defense systems [J].

Chavakis, T ;

Wiechmann, K ;

Preissner, KT ;

Herrmann, M .

THROMBOSIS AND HAEMOSTASIS, 2005, 94 (02) :278-285

[5] Surface adhesins of Staphylococcus aureus [J].

Clarke, Simon R. ;

Foster, Simon J. .

ADVANCES IN MICROBIAL PHYSIOLOGY, VOL 51, 2006, 51 :187-225

[6] CACO-2 AND IEC-18 INTESTINAL EPITHELIAL-CELLS EXERT BACTERICIDAL ACTIVITY THROUGH AN OXIDANT-DEPENDENT PATHWAY [J].

DEITCH, EA ;

HASKEL, Y ;

CRUZ, N ;

XU, DZ ;

KVIETYS, PR .

SHOCK, 1995, 4 (05) :345-350

[7] Fibronectin binding protein and host cell tyrosine kinase are required for internalization of Staphylococcus aureus by epithelial cells [J].

Dziewanowska, K ;

Patti, JM ;

Deobald, CF ;

Bayles, KW ;

Trumble, WR ;

Bohach, GA .

INFECTION AND IMMUNITY, 1999, 67 (09) :4673-4678

[8]

FLOTTE TR, 1993, J BIOL CHEM, V268, P3781

[9] Cellular invasion by Staphylococcus aureus involves a fibronectin bridge between the bacterial fibronectin-binding MSCRAMMs and host cell β1 integrins [J].

Fowler, T ;

Wann, ER ;

Joh, D ;

Johansson, SA ;

Foster, TJ ;

Höök, M .

EUROPEAN JOURNAL OF CELL BIOLOGY, 2000, 79 (10) :672-679

[10] A global view of Staphylococcus aureus whole genome expression upon internalization in human epithelial cells [J].

Garzoni, Christian ;

Francois, Patrice ;

Huyghe, Antoine ;

Couzinet, Sabine ;

Tapparel, Caroline ;

Charbonnier, Yvan ;

Renzoni, Adriana ;

Lucchini, Sacha ;

Lew, Daniel P. ;

Vaudaux, Pierre ;

Kelley, William L. ;

Schrenzel, Jacques .

BMC GENOMICS, 2007, 8 (1)

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