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Staphylococcus aureus host cell invasion and post-invasion events
被引:122
|作者:
Sinha, Bhanu
[1
]
Fraunholz, Martin
[2
]
机构:
[1] Univ Wurzburg, Inst Hyg & Microbiol, D-97080 Wurzburg, Germany
[2] Ernst Moritz Arndt Univ Greifswald, FunGene Competence Ctr Funct Genom, D-17487 Greifswald, Germany
关键词:
Staphylococcus aureus;
Invasion;
Phagosomal escape;
Intracellular persistence;
Host cell death;
alpha-Toxin;
FIBRONECTIN-BINDING PROTEINS;
HUMAN ENDOTHELIAL-CELLS;
EPITHELIAL-CELLS;
ALPHA-TOXIN;
VIRULENCE FACTORS;
HUMAN KERATINOCYTES;
NASAL COLONIZATION;
HUMAN NEUTROPHILS;
TEICHOIC-ACIDS;
DEATH PATHWAY;
D O I:
10.1016/j.ijmm.2009.08.019
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
Staphylococcus aureus is now recognized as a facultative intracellular pathogen. The aim of this review is to discuss novel data regarding the invasion mechanism and post-invasion events with a focus on the fate of the infected phagosome in non-professional phagocytes and the role of S. aureus alpha-toxin. (C) 2009 Elsevier GmbH. All rights reserved.
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页码:170 / 175
页数:6
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