The Role of Dexamethasone Implant in the Management of Tubercular Uveitis

被引：33

作者：

Agarwal, Aniruddha ^{[1
]}

Handa, Sabia ^{[1
]}

Aggarwal, Kanika ^{[1
]}

Sharma, Mansi ^{[1
]}

Singh, Ramandeep ^{[1
]}

Sharma, Aman ^{[2
]}

Agrawal, Rupesh ^{[3
,4
]}

Sharma, Kusum ^{[5
]}

Gupta, Vishali ^{[1
]}

机构：

[1] Post Grad Inst Med Educ & Res, Adv Eye Ctr, Chandigarh, India

[2] Post Grad Inst Med Educ & Res, Dept Internal Med, Chandigarh, India

[3] Tan Tock Seng Hosp, Natl Healthcare Grp Eye Inst, Singapore, Singapore

[4] Moorfields Eye Hosp, NHS Fdn Trust, London, England

[5] Post Grad Inst Med Educ & Res, Div Mycobacteriol, Dept Microbiol, Chandigarh, India

来源：

OCULAR IMMUNOLOGY AND INFLAMMATION | 2018年 / 26卷 / 06期

关键词：

Cystoid Macular Edema; Dexamethasone Implant; Intraocular Tuberculosis; Ozurdex; Retinal Vasculitis; Serpiginous Choroiditis; TB; SERPIGINOUS-LIKE CHOROIDITIS; INTRAOCULAR TUBERCULOSIS; OCULAR TUBERCULOSIS; THERAPY;

D O I：

10.1080/09273948.2017.1400074

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To study the safety and efficacy of intravitreal injection of dexamethasone implant in the management of posterior segment involvement in tubercular uveitis (TBU).Methods: In this study, retrospective analysis of safety and efficacy of intravitreal injection of dexamethasone implant for various indications such as cystoid macular edema (CME), vitritis, or paradoxical worsening in TB-related intermediate uveitis, retinal vasculitis, and multifocal serpiginoid choroiditis (MSC) was performed.Results: The study included 17 patients (19 eyes; 7 males). IOP increased from 14.882.68mm Hg to 16.4 +/- 5.82mm Hg (p=0.18) at 3months. BCVA improved from 0.37 +/- 0.35 to 0.27 +/- 0.21 at 3months (p=0.03). CME resolved at 3months and two patients with paradoxical worsening showed resolution within 1month.Conclusion: Intravitreal dexamethasone implant is safe and efficacious as an adjunct to ATT in reducing the central macular thickness, vitritis, and progression of choroiditis lesions in paradoxical worsening of MSC.

引用

页码：884 / 892

页数：9

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