Regio- and stereoselective ruthenium-catalyzed hydrovinylation of 1,3-dienes:: Application to the generation of a 20(S) steroidal side chain

被引：44

作者：

He, ZJ ^{[1
]}

Yi, CS ^{[1
]}

Donaldson, WA ^{[1
]}

机构：

[1] Marquette Univ, Dept Chem, Milwaukee, WI 53201 USA

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 09期

关键词：

D O I：

10.1021/ol030031+

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of ethylene to 1,3-dienes and 1-vinylcycloalkenes, catalyzed by two ruthenium complexes, proceeds in a regioselective fashion to afford 3-methyl-1,4-dienes as products. For a steroidal-based 1-vinylcycloalkene, the addition is stereospecific, giving a product with a 20(S) configuration.

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页码：1567 / 1569

页数：3

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