Regio- and stereoselective ruthenium-catalyzed hydrovinylation of 1,3-dienes:: Application to the generation of a 20(S) steroidal side chain

被引：44
作者：
He, ZJ [1 ]
Yi, CS [1 ]
Donaldson, WA [1 ]
机构：
[1] Marquette Univ, Dept Chem, Milwaukee, WI 53201 USA
来源：
ORGANIC LETTERS | 2003年 / 5卷 / 09期
关键词：
D O I：
10.1021/ol030031+
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The addition of ethylene to 1,3-dienes and 1-vinylcycloalkenes, catalyzed by two ruthenium complexes, proceeds in a regioselective fashion to afford 3-methyl-1,4-dienes as products. For a steroidal-based 1-vinylcycloalkene, the addition is stereospecific, giving a product with a 20(S) configuration.
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页码：1567 / 1569
页数：3
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