Protein methylation and DNA repair

被引：43
|
作者：
Lake, Aimee N. [1 ]
Bedford, Mark T. [1 ]
机构：
[1] Univ Texas, MD Anderson Canc Ctr, Div Sci Pk Res, Smithville, TX 78957 USA
来源：
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS | 2007年 / 618卷 / 1-2期
关键词：
arginine methylation; lysine methylation; tudor domain; chromo domain; P53; 53BP1; PHF20;
D O I：
10.1016/j.mrfmmm.2006.09.010
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
DNA is under constant attack from intracellular and external mutagens. Sites of DNA damage need to be pinpointed so that the DNA repair machinery can be mobilized to the proper location. The identification of damaged sites, recruitment of repair factors, and assembly of repair "factories" is orchestrated by posttranslational modifications (PTMs). These PTMs include phosphorylation, ubiquitination, sumoylation, acetylation, and methylation. Here we discuss recent data surrounding the roles of arginine and lysine methylation in DNA repair processes. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码：91 / 101
页数：11
相关论文
共 50 条
  • [1] Cytosine methylation and DNA repair
    Walsh, CP
    Xu, GL
    DNA METHYLATION: BASIC MECHANISMS, 2006, 301 : 283 - 315
  • [2] DNA Damage Repair and DNA Methylation in the Kidney
    Hayashi, Kaori
    Hishikawa, Akihito
    Itoh, Hiroshi
    AMERICAN JOURNAL OF NEPHROLOGY, 2019, 50 (02) : 81 - 91
  • [3] The role of protein arginine methylation 5 in DNA damage repair and cancer therapy
    Qikun Gao
    Ziyi Liu
    Jinyang Liu
    Xuyang Yan
    Junfei Dai
    Zixuan Zhang
    Rongxiao Li
    Shiva Basnet
    Changzheng Du
    Genome Instability & Disease, 2023, 4 (6) : 305 - 314
  • [4] DNA methylation reprogramming and DNA repair in the mouse zygote
    Lepikhov, Konstantin
    Wossidlo, Mark
    Arand, Julia
    Walter, Joern
    INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 2010, 54 (11-12): : 1565 - 1574
  • [5] DNA DAMAGE REPAIR AND DNA METHYLATION IN THE KIDNEY AND CKD
    Hayashi, Kaori
    Itoh, Hiroshi
    JOURNAL OF HYPERTENSION, 2023, 41 : E87 - E87
  • [6] The repair of DNA methylation damage in Saccharomyces cerevisiae
    Xiao, W
    Chow, BL
    Rathgeber, L
    CURRENT GENETICS, 1996, 30 (06) : 461 - 468
  • [7] DNA damage, homology-directed repair, and DNA methylation
    Cuozzo, Concetta
    Porcellini, Antonio
    Angrisano, Tiziana
    Morano, Annalisa
    Lee, Bongyong
    Di Pardo, Alba
    Messina, Samantha
    Iuliano, Rodolfo
    Fusco, Alfredo
    Santillo, Maria R.
    Muller, Mark T.
    Chiariotti, Lorenzo
    Gottesman, Max E.
    Avvedimento, Enrico V.
    PLOS GENETICS, 2007, 3 (07): : 1144 - 1162
  • [8] DNA METHYLATION, MISMATCH REPAIR AND GENETIC STABILITY
    RADMAN, M
    MUTATION RESEARCH, 1982, 96 (01): : 142 - 144
  • [9] A new role for arginine methylation in DNA repair
    Boisvert, FM
    Déry, U
    Masson, JY
    Richard, S
    M S-MEDECINE SCIENCES, 2005, 21 (6-7): : 579 - 581
  • [10] The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice
    Langie, Sabine A. S.
    Cameron, Kerry M.
    Ficz, Gabriella
    Oxley, David
    Tomaszewski, Bartlomiej
    Gorniak, Joanna P.
    Maas, Lou M.
    Godschalk, Roger W. L.
    van Schooten, Frederik J.
    Reik, Wolf
    von Zglinicki, Thomas
    Mathers, John C.
    GENES, 2017, 8 (02)
12345