Visual phosphene perception modulated by subthreshold crossmodal sensory stimulation

被引：61

作者：

Ramos-Estebanez, Ciro ^{[1
]}

Merabet, Lotfi B. ^{[1
]}

Machii, Katsuyuki ^{[1
]}

Fregni, Felipe ^{[1
]}

Thut, Gregor ^{[1
]}

Wagner, Timothy A. ^{[1
]}

Romei, Vicenzo ^{[1
]}

Amedi, Amir ^{[1
]}

Pascual-Leone, Alvaro ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Berenson Allen Ctr Noninvas Brain Stimulat, Boston, MA 02215 USA

来源：

JOURNAL OF NEUROSCIENCE | 2007年 / 27卷 / 15期

关键词：

phosphenes; crossmodal; subthreshold; tactile; visual cortex; TMS;

D O I：

10.1523/JNEUROSCI.5468-06.2007

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Crossmodal sensory interactions serve to integrate behaviorally relevant sensory stimuli. In this study, we investigated the effect of modulating crossmodal interactions between visual and somatosensory stimuli that in isolation do not reach perceptual awareness. When a subthreshold somatosensory stimulus was delivered within close spatiotemporal congruency to the expected site of perception of a phosphene, a subthreshold transcranial magnetic stimulation pulse delivered to the occipital cortex evoked a visual percept. The results suggest that under subthreshold conditions of visual and somatosensory stimulation, crossmodal interactions presented in a spatially and temporally specific manner can sum up to become behaviorally significant. These interactions may reflect an underlying anatomical connectivity and become further enhanced by attention modulation mechanisms.

引用

页码：4178 / 4181

页数：4

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